The American Journal of Human Genetics
Volume 108, Issue 3, 4 March 2021, Pages 446-457
ArticleLoss of α-actinin-3 during human evolution provides superior cold resilience and muscle heat generation
Under a Creative Commons license
open access
Keywords
alpha-actinin-3 deficincy
energy efficient thermogenesis
improved cold tolerance
skeletal muscle
muscle fiber type
brown adipose tissue
evolutionary advantage
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