Cell Metabolism
Volume 33, Issue 3, 2 March 2021, Pages 462-463
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How does obesity promote breast cancer tumor growth?

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Obesity is a risk factor for many cancers. Maguire et al. (2021) found increased creatine synthesis by the adipocytes adjacent to breast cancers in obese mice. The creatine is transported into the cancer cells, producing larger tumors, possibly due to greater energy availability.

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