Journal of Biological Chemistry
Volume 296, January–June 2021, 100705
JBC ReviewsThere’s more to death than life: Noncatalytic functions in kinase and pseudokinase signaling
Under a Creative Commons license
open access
Keywords
pseudoenzyme
dead enzyme
nonenzyme
protein kinase
protein structure
Abbreviations
BUBR1
BUB1 related-1
DSF
differential scanning fluorimetry
EGFR
epidermal growth factor receptor
HDX-MS
hydrogen-deuterium exchange mass spectrometry
HER
Receptor tyrosine-protein kinase erbB
ILK
integrin-linked kinase
IRAK
IL-1 receptor-associated kinase
JAK
Janus kinase
KSR
kinase suppressor of Ras
MEK1
MAPK/ERK kinase 1
MLKL
mixed lineage kinase domain-like
PABPs
poly(A)-binding proteins
PEAK
pseudopodium-enriched atypical kinase
PK-1
protein kinase-1
PsK
pseudokinase
RAF
rapidly accelerated fibrosarcoma kinase
RIPK
receptor interacting serine/threonine kinase
RKS1
resistance-related kinase 1
SgK
Sugen kinase
TRIB
Tribbles family pseudokinase
ULK4
Unc-51-like kinase 4
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© 2021 The Authors. Published by Elsevier Inc on behalf of American Society for Biochemistry and Molecular Biology.