A simple and efficient procedure for the synthesis of benzimidazoles using air as the oxidant
Graphical abstract
Direct one-step synthesis of various benzimidazoles from phenylenediamines and aldehydes is described using air as the oxidant. The salient features of this method include a simple procedure, mild conditions, no coupling agents or commercial oxidants/additives used, no waste produced (only by-product being water), easy purification, and high generality.
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Acknowledgements
We would like to thank Drs. Min Ge, Changyou Zhou, and Alexander Pasternak for helpful discussions.
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