Original articlesPseudoexfoliation syndrome in Australian adults☆
Section snippets
Methods
Details of the methodology for the Visual Impairment Project have been published previously.20 Briefly, cluster, stratified random sampling was employed to identify a cohort representative of the population of the state of Victoria, Australia, who were aged 40 years and older. The study cohort comprised nine pairs of urban census collector districts, 14 nursing homes, and four pairs of rural census collector districts. The nursing home and rural areas were oversampled relative to the urban
Results
A total of 3,271 of the urban residents (83% of eligible), 403 nursing home residents (90% of eligible), and 1,473 rural residents (92% of eligible) participated. Nonparticipants did not differ from participants in any way likely to bias these results.26 Non–English-speaking residents were significantly less likely to participate than English-speaking residents (odds ratio = 0.60, 95% confidence limit = 0.44, 0.81). However, the rate of participation was fairly high in all language groups
Discussion
Pseudoexfoliation syndrome was found to be a relatively common condition, affecting 6% of people in their eighties. The overall rate of 0.98% (95% confidence limit, 0.57, 1.28) in the Visual Impairment Project is slightly less than the rates reported in the Framingham Eye Study (1.8%)15 and the Blue Mountains Eye Study (2.3%),18 but the Visual Impairment Project study population is younger than the other two studies, so the rates are not directly comparable. The Framingham Eye Study and the
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The Visual Impairment Project was funded in part by grants from the National Health and Medical Research Council, Woden, ACT, the Victorian Health Promotion Foundation, Melbourne, VIC, the estate of the late Dorothy Edols, Melbourne, VIC, and the Jack Brockhoff Foundation, Melbourne, VIC. Dr McCarty is the recipient of a Wagstaff Fellowship in Ophthalmology from the Royal Victorian Eye and Ear Hospital, Melbourne, VIC.