Research reportThe relationship between monkey ventrolateral thalamic nucleus activity and kinematic parameters of wrist movement
References (38)
- et al.
Distribution of cerebellar terminations and their relation to other afferent terminations in the ventral lateral thalamic region of the monkey
Brain Res. Reu.
(1983) - et al.
Interpositus neuron discharge in relation to a voluntary movement
Brain Res.
(1977) - et al.
Mode of operation of the cerebellum in the dynamic loop control of movement
Brain Res.
(1972) Cumulative sum technique and its application to the analyses of peristimulus time histograms, Electroencephalogr
Electroencephalogr. Clin. Neurophysiol.
(1978)- et al.
The role of the cerebelao-thalamocortical pathway in skilled movement
Prog. Brain Res.
(1995) Unit activity in the cerebellar nuclei related to arm reaching movements
Brain Res.
(1988)- et al.
Cerebellar modulation of reflex gain
Prog. Neurobiol.
(1979) The actiuity of neurones in the cerebellum in relation to kinematics of movement, and the organisation of the cerebellothalamic pathway
- et al.
The relationship between monkey dentate cerebellar nucleus activity and kinematic parameters of wrist movement
J. Neurophysiol.
(1996) - et al.
Effect of cooling dentate nucleus on tracking-task performance in monkeys
J. Neurophysiol.
(1973)
Centrally influenced activity in the monkey ventrolateral thalamus during interactive involuntary and voluntary wrist movements
Exp. Brain Res.
A frequency analysis of neuronal activity in monkey thalamus, motor cortex and electromyograms in wrist oscillations
J. Phvsiol.
The activity of monkey thalamic and motor cortical neurones in a skilled, ballistic movement
J. Physiol.
Sensory characteristics of monkey thalamic and motor cortex neurones
J. Physiol.
Activity of dentate neurons during arm movements triggered by visual, auditory, and somesthetic stimuli in the monkey
J. Neurophysiol.
A comparison of methods used to detect changes in neuronal discharge patterns
Are movement parameters recognizably coded in the activity of single neurons?
Relationship of monkey ventrolateral thalamic neurons to the kinematics of movement
Soc. Neurosci. Abstr.
Relations of motor cortex neural discharge to kinematics of passive and active elbow movements in the monkey
J. Neurophysiol.
Cited by (13)
Oscillatory waveform sharpness asymmetry changes in motor thalamus and motor cortex in a rat model of Parkinson's disease
2022, Experimental NeurologyCitation Excerpt :The Mthal comprises a group of ventral thalamic nuclei (ventroanterior [VA], ventromedial [VM] and ventrolateral [VL] thalamus) that receive afferents from basal ganglia or cerebellum (Ilinsky and Kultas-Ilinsky, 2001; Krack et al., 2002; Bosch-Bouju et al., 2013). Mthal neurons are modulated prior to or during movement (Strick, 1976; Schmied et al., 1979; Horne and Porter, 1980; Macpherson et al., 1980; Schlag-Rey and Schlag, 1984; Anderson and Turner, 1991; Nambu et al., 1991; Butler et al., 1992; Forlano et al., 1993; Butler et al., 1996; Inase et al., 1996; Raeva et al., 1999; Ivanusic et al., 2005; Kurata, 2005; Kunimatsu and Tanaka, 2010; Gaidica et al., 2018; Tanaka et al., 2018; Sauerbrei et al., 2020) and are essential for initiating goal-directed movements (Dacre et al., 2021; Takahashi et al., 2021), potentially by increasing the gain and bursting of layer V pyramidal neurons (Larkum et al., 2004; Park et al., 2020). Accordingly, Mthal occupies a central position in early (Albin et al., 1989; Alexander and Crutcher, 1990; DeLong, 1990; DeLong and Wichmann, 2007) and more recent (Bosch-Bouju et al., 2013; Magnusson and Leventhal, 2021) theories linking neurophysiological changes in basal ganglia nuclei with the movement deficits of PD.
A cerebellar-thalamocortical pathway drives behavioral context-dependent movement initiation
2021, NeuronCitation Excerpt :Two distinct pathways could contribute to movement initiation, the cerebellar-rubrospinal tract (Asanuma et al., 1983; Gibson et al., 1985; Teune et al., 2000) or the cerebellar-thalamocortical pathway (Bostan et al., 2013; Gornati et al., 2018; Horne and Butler, 1995; Kuramoto et al., 2009; Nashef et al., 2019). The latter is supported by neuronal activity in dentate/interpositus nuclei (DN/IPN) and recipient motor thalamic regions preceding cortical activity (Nashef et al., 2018; Strick, 1976; Thach, 1975, 2014) and movement initiation (Anderson and Turner, 1991; Butler et al., 1992, 1996; Fortier et al., 1989; Harvey et al., 1979; Horne and Porter, 1980; Kurata, 2005; Macpherson et al., 1980; Mushiake and Strick, 1993; Schmied et al., 1979; Strick, 1976; van Donkelaar et al., 1999), while disrupting activity in either region alters the timing of sensory-triggered actions (Meyer-Lohmann et al., 1977; Nashef et al., 2019; Spidalieri et al., 1983; Thach, 1975; van Donkelaar et al., 2000). Beyond a proposed role in movement initiation, DN/IPN and recipient regions of motor thalamus coordinate the timing and accuracy of ongoing movements given that focal inactivation alters endpoint accuracy (dysmetria/hypermetria), reach path curvature and grasping (Becker and Person, 2019; Bracha et al., 1999; Butler et al., 1992; Cooper et al., 2000; Horne and Butler, 1995; Ishikawa et al., 2014; Martin et al., 2000; Mason et al., 1998; Thanawalla et al., 2020), and loss of anticipatory limb adjustments to unexpected obstacles during complex locomotion (Martin et al., 2000; Milak et al., 1997).
Cerebellar thalamic activity in the macaque monkey encodes the duration but not the force or velocity of wrist movement
2005, Brain ResearchCitation Excerpt :Thus, the CTC may provide a temporal and spatial “spotlight” onto motor cortex, selecting regions required to perform multijoint movements rather than providing information pertaining to specific parameters such as force or velocity. While single trial analyses using tools such as the KBSTA to identify onset and offset of neuronal activity improved the likelihood of establishing significant correlations between neuronal discharge and movement parameters (e.g., in the case of duration of movement vs. the duration of cerebellar thalamic discharge from 15% in Butler et al. [15] to 58% in the present study), it is likely that a population of neurones will provide greater information content and thus more robust correlations. A number of groups have analysed retrospectively constructed neuronal ensembles to investigate the behaviour of neuronal populations, but only a few have done so in motor systems.
A comparison of methods used to detect changes in neuronal discharge patterns
1997, Journal of Neuroscience MethodsReduced reach-related modulation of motor thalamus neural activity in a rat model of parkinson’s disease
2014, Journal of NeuroscienceMotor thalamus integration of cortical, cerebellar and basal ganglia information: Implications for normal and parkinsonian conditions
2013, Frontiers in Computational Neuroscience