The distribution of estrogen receptors in the brainstem of female sheep1
Section snippets
Acknowledgements
This work was supported by the National Health and Medical Research Council of Australia.
References (14)
- et al.
Differential expression of estrogen receptor and neuropeptide Y by brainstem A1 and A2 noradrenaline neurons
Neuroscience
(1997) - et al.
Production of monoclonal antibodies to human estrogen-receptor protein (ER) using recombinant ER (RER)
Int. J. Cancer
(1993) - et al.
The role of catecholamines in the regulation of pituitary luteinizing hormone and follicle-stimulating hormone secretion
Endocrinol. Rev.
(1982) - et al.
Topographic organisation of cardiovascular responses to electrical and glutamate microstimulation of the parabrachial nucleus in the rat
J. Comp. Neurol.
(1992) - Clarke, I.J., Effector mechanisms of the hypothalamus that regulate the anterior pituitary gland. In K. Unsicker (Ed.),...
- Clarke, I.J., Pereira, A., Rawson, J.A. and Scott, C.J., Loss of terminal staining for dopamine β hydroxylase (DBH) in...
Neurochemical identity of neurones expressing oestrogen and androgen receptors in sheep hypothalamus
J. Reprod. Fertil. Suppl.
(1995)
Cited by (27)
Estrogen Regulation of Neurotransmitter and Growth Factor Signaling in the Brain
2017, Hormones, Brain and Behavior: Third EditionSex differences in the expression of estrogen receptor alpha within noradrenergic neurons in the sheep brain stem
2014, Domestic Animal EndocrinologyCitation Excerpt :In that study, nearly 100% of retrogradely labeled cells in the A1 region were DBH-ir, and because in our study the number of ERα/DBH-double labeled cells in the ram was essentially the same as in the ewe, it seems most likely that the same pathway as described in the ewe exists in the ram, possibly with similar numbers of neurons. Previous data from the ewe suggest that ERα within noradrenergic cells in the A1 region have a role in the positive feedback actions of estrogen on GnRH/LH secretion [10–18]. Based on this, we hypothesized that there would be a population of cells present in the ewe but absent in the ram and these may be partially responsible for relaying the positive feedback actions of estrogen.
Estradiol-17β-responsive A1 and A2 noradrenergic cells of the brain stem project to the bed nucleus of the stria terminalis in the ewe brain: A possible route for regulation of gonadotropin releasing hormone cells
2010, NeuroscienceCitation Excerpt :Interestingly, cells of the PBN that project to the BNST did not contain ERα and are thus unlikely to participate in the feedback regulation of GnRH neurons. This is in spite of the fact that this region of the ovine brain contains many cells that express ERα (Scott et al., 1998). Also, in rats, cells of this nucleus, especially in the lateral regions, express ERα and ERβ (Simerly et al., 1990; Saleh et al., 2003).
Estrogen regulation of neurotransmitter and growth factor signaling in the brain
2009, Hormones, Brain and Behavior OnlineDevelopment of ER-α and ER-β expression in the developing ovine brain and pituitary
2008, Gene Expression Patterns
- 1
Part of this work was presented at the 30th Annual Meeting of the Australian Society for Reproductive Biology, Canberra, Australia 1997, and the 27th Annual Meeting of the Society for Neuroscience, New Orleans, USA, 1997.