Trends in Microbiology
Volume 7, Issue 8, 1 August 1999, Pages 328-333
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Review
Apicomplexan plastids as drug targets

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Abstract

Prokaryotic metabolic pathways in the relict plastid of apicomplexan parasites make this organelle a promising target for drug development. The parasiticidal activity of several herbicides and antibacterial antibiotics is suspected to be a result of their ability to inhibit key plastid activities.

Keywords

Microbiology
Pharmacology
Parasitology
Evolution
Cell biology

Keywords

Malaria
Toxoplasmosis
Plastid
Endosymbiosis
Apicoplast

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