Immunity
Volume 18, Issue 5, May 2003, Pages 583-584
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Hide and Seek: The Immunology of HSV Persistence

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Abstract

Herpes simplex virus (HSV) has been thought to persist as a latent infection by completely extinguishing antigen expression. In this issue of Immunity, Khanna et al. challenge this view by showing that CTL specific for antigens normally associated with active viral replication are crucial participants in regulating virus latency.

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