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Death and disability: the outcomes of tuberculous meningitis

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Cited by (28)

  • Forty years of Tuberculous meningitis: The new face of an old enemy

    2020, International Journal of Infectious Diseases
    Citation Excerpt :

    This is a paradox since the diagnostic methods available are becoming faster and more reliable and lead us to think that low clinical suspicion delays the performance of lumbar puncture and the beginning of adequate empirical treatment. This delay, in turn, leads to an increase in mortality and sequelae associated with TBM, as already described (Graham and Donald, 2014; Lu et al., 2001; Hosoglu et al., 2002). On the other hand, our series' data does not show susceptibility issues to first-line TB drugs.

  • Tuberculous meningitis manifesting with neuroregression in a eleven month child

    2020, Indian Journal of Tuberculosis
    Citation Excerpt :

    There were no significant findings in other systems. With the above scenario, MRI brain (Fig. 1) was done which revealed basal exudates, non-obstructive hydrocephalus and tubercles in the brain stem suggestive of tubercular meningitis.3 The child was investigated further with lumbar puncture, and CSF(Cerebro Spinal Fluid) showed moderately elevated protein (173 mg/dl)and a mild decrease in glucose (30 mg/dl), with predominance of lymphocytes (270 cells/cu mm, 90% were lymphocytes).

  • <sup>1</sup>H nuclear magnetic resonance-based metabolic profiling of cerebrospinal fluid to identify metabolic features and markers for tuberculosis meningitis

    2019, Infection, Genetics and Evolution
    Citation Excerpt :

    It is associated with the highest rates of morbidity and mortality among all forms of tuberculosis in adults and children (Wilkinson et al., 2017). The outcome is often grave, involving substantial neurological sequelae or death (Chiang et al., 2014; Graham and Donald, 2014). Early diagnosis and initiation of the appropriate treatment at an optimal dose can greatly improve the clinical outcome of TBM (Török, 2015).

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