Original articleDeterminants of Lens Vault and Association With Narrow Angles in Patients From Singapore
Section snippets
Study Population
This was a cross-sectional study of persons aged 50 years and older who were recruited between December 7, 2005 and July 12, 2006 from a government-run polyclinic in Singapore that provides primary healthcare services for residents living in the area around the clinic. Details of the study have been described previously.12, 13 In brief, subjects were identified by systematic sampling (every fifth patient registered at the polyclinic) and asked to participate in the study after obtaining written
Results
A total of 2047 participants were recruited into the study. Among them, 582 subjects were excluded for the following reasons: 11 subjects could not undergo gonioscopy; 62 subjects did not complete AS-OCT examination or had poor quality AS-OCT images; 42 subjects showed software delineation errors; and the scleral spur was not clearly visible on AS-OCT images in 467 subjects. There were no significant differences between included and excluded subjects regarding race, spherical equivalent
Discussion
We found that lens vault is strongly associated with narrow angles in this Singapore Chinese population. Lens vault measures the extent of anterior projection of the lens over the level of the scleral spurs but AS-OCT is unable to assess the posterior portion of the lens (or the zonules or ciliary body). Since lens vault will be affected by both lens thickness and lens position, it serves as a measure that encompasses the effect of both parameters. This is important as individually each
References (26)
- et al.
Acute primary angle closure in an Asian population: long-term outcome of the fellow eye after prophylactic laser peripheral iridotomy
Ophthalmology
(2000) - et al.
Lens vault, thickness, and position in Chinese subjects with angle closure
Ophthalmology
(2011) - et al.
Novel association of smaller anterior chamber width with angle closure in Singaporeans
Ophthalmology
(2010) - et al.
Long-term outcomes in Asians after acute primary angle closure
Ophthalmology
(2004) - et al.
Detection of narrow angles and established angle closure in Chinese residents of Singapore: potential screening tests
Am J Ophthalmol
(2006) - et al.
Optical and ultrasound measurement of axial length and anterior chamber depth for intraocular lens power calculation
J Cataract Refract Surg
(2003) - et al.
Comparison and evaluation of ocular biometry using a new noncontact optical low-coherence reflectometer
Ophthalmology
(2009) - et al.
The number of people with glaucoma worldwide in 2010 and 2020
Br J Ophthalmol
(2006) - et al.
The epidemiology of age related eye diseases in Asia
Br J Ophthalmol
(2006) - et al.
The prevalence of glaucoma in Chinese residents of Singapore: a cross-sectional population survey of the Tanjong Pagar district
Arch Ophthalmol
(2000)
Interventions for angle-closure glaucoma: an evidence-based update
Ophthalmology
Aetiology of the anatomical basis for primary angle-closure glaucomaBiometrical comparisons between normal eyes and eyes with primary angle-closure glaucoma
Br J Ophthalmol
Ocular parameters in the subgroups of angle closure glaucoma
Clin Experiment Ophthalmol
Cited by (52)
Lens-vault analysis and its correlation with other biometric parameters using swept-source OCT
2022, Journal of OptometryCitation Excerpt :They concluded that once LV goes above a given threshold for that particular ethnicity, angle narrowing tends to occur. Tan et al.11 found that there were no association between LV and race, and concluded that LV was independently associated with the presence of narrow angles and showed good diagnostic performance in detecting eyes with narrow angles. In contrast, Lee et al.18 reported that ethnic variation in anterior segment biometric parameters exists.
A Deep Learning System for Automated Angle-Closure Detection in Anterior Segment Optical Coherence Tomography Images
2019, American Journal of OphthalmologyComparison of Anterior Segment Optical Coherence Tomography Parameters Among Vietnamese, Chinese, and Whites
2018, American Journal of OphthalmologyCitation Excerpt :These findings may suggest that Vietnamese eyes had predisposing smaller anterior chamber configurations than Chinese and this anatomic aspect may combine with other factors to cause a more crowded angle. Shallow ACD and LV have been shown to be independent risk factors for angle closure in multiple ethnicities, including Chinese.23–26 Our study found that, in angle closure eyes, Vietnamese subjects had higher LV compared to Chinese.
Clear lens extraction in eyes with primary angle closure and primary angle-closure glaucoma
2020, Survey of OphthalmologyComparison of Anterior Segment Parameters among Koreans, Chinese, and White Persons
2018, Ophthalmology GlaucomaCorrelation between Intraocular Pressure and Angle Configuration Measured by OCT: The Chinese American Eye Study
2018, Ophthalmology Glaucoma