Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms
Volume 1861, Issue 12, December 2018, Pages 1093-1101
Specificity of MLL1 and TET3 CXXC domains towards naturally occurring cytosine modifications
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Abbreviations
MLL
mixed lineage leukemia
TET
ten-eleven translocation
MBD
methylated CpG binding domain
CGI
CpG island
C
cytosine
5mC
5-methylcytosine
5hmC
5-hydroxymethylcytosine
5fC
5-formylcytosine
5caC
5-carboxylcytosine
H3K4me1
H3K4 monomethylation
H3K4me3
H3K4 trimethylation
PC
pocket C
PG
pocket G
PG*
pocket G*
PC*
pocket C*
MLL1-CXXC
human MLL1 CXXC domain
TET3-CXXC
human TET3 CXXC domain
PBM
protein binding microarray
BER
base excision repair
EMSA
electrophoretic mobility shift assay
Keywords
CXXC domain
Mixed lineage leukemia (MLL)
K-specific methyltransferase (KMT2)
Ten-eleven-translocation (TET)
CpG island (CGI)
Cytosine modifications
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© 2018 The Authors. Published by Elsevier B.V.