Cell
Volume 150, Issue 2, 20 July 2012, Pages 245-247
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The Split Personality of CENP-A Nucleosomes

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The composition and structure of centromeric nucleosomes, which contain the histone H3 variant CENP-A, is intensely debated. Two independent studies in this issue, in yeast and human cells, now suggest that CENP-A nucleosomes adopt different structures depending on the stage of the cell cycle.

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