Chem
Volume 6, Issue 8, 6 August 2020, Pages 1853-1855
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Bioorthogonal Catalysis Goes Chiral

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Bioorthogonal nanofactories have emerged in the last decade to provide xenobiotic pathways that generate nonbiological substances in living environments. In this issue of Chem, Qu and co-workers incorporate asymmetric catalytic properties and chemotactic capabilities into novel nanodevices to achieve the stereo- and site-selective synthesis of the active enantiomer of ibuprofen at inflammation sites.

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