Chest
Evidence-Based MedicineEtiologies of Chronic Cough in Pediatric Cohorts: CHEST Guideline and Expert Panel Report
Section snippets
Summary of Recommendations and Suggestions
1. For children aged ≤ 14 years, we recommend that common etiologies of chronic cough in adults are not presumed to be common causes in children (Level 1B).
2. For children aged ≤ 14 years with chronic cough, we recommend that their age and the clinical settings (eg, country and region) are taken into consideration when evaluating and managing their chronic cough (Level 1B).
3. For children aged ≤ 14 years with chronic cough, we suggest that clinical studies aimed at evaluating cough etiologies
Methods
We undertook the systematic reviews based on the protocol16 established by selected members of the CHEST Expert Cough Panel. We used the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement for reporting. The KQs were framed by this paper’s main authors.
Results
The search results and PRISMA diagrams for all KQs are presented in e-Figures 1 and 2.
Acknowledgments
Financial/nonfinancial disclosures: The authors have reported to CHEST the following: A. B. C. was an author of several of the papers included in this review, is an author and reviewer for Up to Date, was on the data safety monitoring board for a vaccine study (Glaxo), and has been an advisor for the study design of an unlicensed product (Merck). J. J. O. is on the Board of Directors for the American Board of Allergy and Immunology, is associate editor for the Annals of Allergy Watch, has been
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DISCLAIMER: American College of Chest Physician guidelines are intended for general information only, are not medical advice, and do not replace professional medical care and physician advice, which always should be sought for any medical condition. The complete disclaimer for this guideline can be accessed at http://www.chestnet.org/Guidelines-and-Resources/Guidelines-and-Consensus-Statements/CHEST-Guidelines.
FUNDING/SUPPORT: A. B. C. is supported by a National Health and Medical Research Council (NHMRC) practitioner fellowship [Grant 1058213] and holds multiple grants awarded from the NHMRC related to diseases associated with pediatric cough. The views expressed in this publication are those of the authors and do not reflect the views of the NHMRC.