Patient Reported Outcome Measures in multiple myeloma: real-time rePorTing to improve care (My-PROMPT) - a pilot randomised controlled trial

Background

Multiple myeloma (MM) is associated with high burden of disease, compromising patients' health-related quality of life (HRQOL). Whether incorporating patient reported outcome (PRO) measures into routine care improves MM outcomes has not been studied. In order to design a clinical trial to evaluate impact of real-time PRO reporting on outcomes, feasibility and acceptability to clinicians and patients of delivering such an intervention needs to be evaluated.

Methods

We performed a pilot, randomised controlled trial to assess feasibility of real-time reporting of PRO in newly diagnosed MM to treating clinicians. The intervention arm completed a disease-specific PRO measure (MyPOS) before 4 clinic visits (T1-4): baseline, 1, 6 and 10 months. Treating clinicians were given a summary of MyPOS results before visits. The control arm completed MyPOS at T1 and 4. Evaluations of the intervention were completed by patients at T3 and clinicians after T1, 2 and 3.

Results

Thirty-two patients were enrolled, 16 randomised to each arm. Baseline characteristics were well matched other than more males in the control arm (81 v 25%, p<0.001). Patients' median satisfaction score for MyPOS use was 5 (1=Not at all satisfied, 5=Very satisfied, n=13), and median satisfaction score for 15 clinicians over T1 to T3 visits (n=39) was 85 (1=Not at all satisfied, 100=Very satisfied). In patient evaluations, 92% felt completing MyPOS helped communicate concerns to doctors, 75%

Conclusion

Findings support feasibility and acceptability of real-time reporting of a PRO measure to clinicians before patient visits and will inform design of a larger, randomised controlled trial to assess health benefits of the intervention, including impact on HRQOL.

Keywords

Patient Reported Measures

Quality of Life

Trial

Tracks

4th Nursing Symposium