Six year incidence and progression of diabetic retinopathy: Results from the Mauritius diabetes complication study
Section snippets
Patients and methods
The population, methods and response rates of the study have been described in detail elsewhere [15], [16]. In brief, for the baseline survey in 1987, a population-based sample of people aged ≥25 years was drawn from 10 randomly selected areas of Mauritius. In 1992 and 1998, all participants were invited for follow-up, as were all other eligible residents in the 10 areas, and in another three purposefully selected areas. The response rates for the surveys were 86% in 1987, 88% in 1992 and 87%
Results
Among those with diabetes (KDM and NDM) and free of retinopathy at baseline, the 6 year incidence of retinopathy (NPDR and PDR) was 23.8% (proliferative in 0.4%; Table 2). In those with KDM at baseline the incidence of NPDR was 29.2% and PDR was 1.0%. In those with NDM at baseline the incidence of NPDR was 19.1% (no incident cases of PDR were found). The incidence of retinopathy increased with longer duration of diabetes; baseline duration <4 years 19.2%, 4–8 years 29.2%, >8 years 66.7%. Among
Conclusions
A limited number of longitudinal population-based studies of diabetic retinopathy have been conducted in developing countries and few studies in general have included those with newly diagnosed diabetes and impaired glucose tolerance. The 6-year incidence of retinopathy in Mauritius was 30.2% among those with KDM at baseline and 19.1% among those with NDM at baseline. The incidence of retinopathy was similar to that found in populations from developed countries [19], [20], [21]. In the
Acknowledgements
This study undertaken with the support and collaboration of the Ministry of Health (Mauritius), the World Health Organisation (Geneva, Switzerland), International Diabetes Institute (Melbourne, Australia), the University of Newcastle upon Tyne (UK), and the National Public Health Institute (Helsinki, Finland). This study was partially funded by US National Institutes of Health Grant DK-25446. R. Tapp is supported by a grant from the National Health and Medical Research Council of Australia
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