Letter to the Editor
Prevalence and risk factors associated with fatal adverse drug reactions among patients admitted at a Spanish teaching hospital

https://doi.org/10.1016/j.ejim.2019.09.011Get rights and content

Highlights

  • •

    The prevalence of drug-related deaths was 0.74% of hospital admissions, and 0.47% in the case of hospital-acquired drugs.

  • •

    The risk factors associated with drug-related deaths were age, admission at the intensive care unit, and length of stay.

  • •

    The AUC ROC value was 0.82 showing a good predictive potential for the risk factors studied.

Section snippets

Declaration of Competing Interests

None.

Funding

This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors.

Acknowledgments

The authors are grateful to Clinical Documentation Department of Hospital Universitario San Cecilio of Granada (Spain), to Carmen Mota Rodríguez, Graduate Nursing, Assistant Professor of the School of Health Sciences of the University of Granada (Spain) and to Ana García Velasco and María Soriano Segura, research fellows of the School of Medicine of the University of Granada (Spain), for their participation in the collection and coding of data.

The authors thank Rob Hughes for improving the

Author declaration

We wish to confirm that there are no known conflicts of interest associated with this publication and there has been no significant financial support for this work that could have influenced its outcome.

We confirm that the manuscript has been read and approved by all named authors and that there are no other persons who satisfied the criteria for authorship but are not listed. We further confirm that the order of authors listed in the manuscript has been approved by all of us.

We confirm that we

References (7)

  • European Commission

    Proposal for a regulation amending, as regards pharmacovigilance of medicinal products for human use. Regulation (EC) no 726/2004

  • J.C. Bouvy et al.

    Epidemiology of adverse drug reactions in Europe: a review of recent observational studies

    Drug Saf

    (2015)
  • A.J. Pardo Cabello et al.

    Drug-related mortality among inpatients: a retrospective observational study

    Eur J Clin Pharmacol

    (2016)
There are more references available in the full text version of this article.

Cited by (2)

View full text
© 2019 European Federation of Internal Medicine. Published by Elsevier B.V. All rights reserved.