Original articleFolliculitis decalvans: Effectiveness of therapies and prognostic factors in a multicenter series of 60 patients with long-term follow-up
Section snippets
Study design
A retrospective multicenter study was designed; it included patients with FD and a minimum follow-up period of 5 years. The study included patients evaluated in 9 Spanish medical centers between 1995 and 2015. The diagnosis of FD was confirmed by histopathology in all patients. The following details of all patients were recorded in a database: epidemiologic (sex, age, race, comorbidities, family history, and associated trigger), clinical (age of onset, size, affected areas, symptoms, signs, and
Results
A total of 60 patients (37 males [61.7%] and 23 females [38.3%]) with a median age of 40 years (range, 23-83) were included in the study. Fifty-eight patients (96.6%) were white, 1 (1.6%) was Hispanic, and 1 (1.6%) was of African origin.
The associated comorbidities were as follows: hypercholesterolemia in 8 patients (13.3%), arterial hypertension in 7 patients (11%), pollen allergy in 3 patients (5%), obesity in 2 patients (3.3%), and non-Hodgkin lymphoma in 1 patient (1.6%). There were no
Discussion
Our study was based on patients with FD and a follow-up period of more than 5 years, and it was intended to deepen the knowledge of this disease. We have proposed a specific therapeutic protocol that could be very useful in the daily practice of the dermatologist (Table I).1, 2, 7, 8, 9
FD affects young patients, with a discrete male predominance.2, 6, 8, 9, 12, 13, 14, 15 In our study, the detected comorbidities and laboratory tests performed reflect the fact that the disease has no association
References (19)
- et al.
[Reference guidelines for the 12-Item Short-Form Health Survey version 2 based on the Catalan general population]
Med Clin
(2012) - et al.
Primary cicatricial alopecias: clinicopathology of 112 cases
J Am Acad Dermatol
(2004) Cicatricial alopecia: clinico-pathological findings and treatment
Clin Dermatol
(2001)- et al.
Treatment of folliculitis decalvans with photodynamic therapy: results in 10 patients
J Am Acad Dermatol
(2015) - et al.
Folliculitis decalvans
Dermatol Ther
(2008) - et al.
Folliculitis decalvans: a multicentre review of 82 patients
J Eur Acad Dermatol Venereol
(2015) - et al.
Immunopathogenesis of folliculitis decalvans: clues in early lesions
Am J Clin Pathol
(2008) - et al.
First evidence of bacterial biofilms in the anaerobe part of scalp hair follicles: a pilot comparative study in folliculitis decalvans
J Eur Acad Dermatol Venereol
(2013) - et al.
Tufted hair folliculitis causing skullcap-pattern cicatricial alopecia
J Eur Acad Dermatol Venereol
(2006)
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Funding sources: None.
Conflicts of interest: None disclosed.
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