Original InvestigationStrain-Guided Management of Potentially Cardiotoxic Cancer Therapy
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Central Illustration
Key Words
cancer therapy–related cardiac dysfunction
cardioprotective therapy
global longitudinal strain
heart failure
Abbreviations and Acronyms
2D
2-dimensional
3D
3-dimensional
ACE
angiotensin-converting enzyme
ARB
angiotensin receptor blocker
CI
confidence interval
CPT
cardio-protective therapy
CTRCD
cancer therapy related cardiac dysfunction
GLS
global longitudinal strain
HER2+
human epidermal growth factor receptor 2 positive
LV
left ventricle
LVEF
left ventricular ejection fraction
RRR
relative risk reduction
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The authors attest they are in compliance with human studies committees and animal welfare regulations of the authors’ institutions and Food and Drug Administration guidelines, including patient consent where appropriate. For more information, visit the Author Center.
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Drs. Thavendiranathan and Negishi contributed equally to this work and are co-first authors.
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Deceased.
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A full list of SUCCOUR investigators is listed in the Appendix.
© 2021 by the American College of Cardiology Foundation. Published by Elsevier.