Research report
Belief in the harmfulness of antidepressants: Results from a national survey of the Australian public

https://doi.org/10.1016/j.jad.2005.06.002Get rights and content

Abstract

Background

Surveys of the public in several countries have found that negative attitudes towards antidepressants are common. However, there has been little research into the factors associated with these attitudes.

Methods

A national survey of 999 Australian adults assessed beliefs about the helpfulness or harmfulness of antidepressants for a person with depression and suicidal thoughts. Associated factors investigated were as follows: sociodemographic characteristics, exposure to depression, ability to recognize depression, beliefs about other depression interventions, beliefs about long-term outcomes with and without treatment, beliefs about causes, and stigmatizing attitudes.

Results

Around a quarter of Australian adults believe that antidepressants would be harmful for a person who is depressed and suicidal. This group was less educated, had less exposure to depression, showed poorer recognition of depression, was less favorable about other standard interventions including psychological ones, was less pessimistic about the long-term outcome if the person did not have treatment, and was more likely to see depression as due to weakness and to be under the individual's control.

Limitations

The survey did not directly ask about reasons for believing that antidepressants would be harmful.

Conclusions

Belief in the harmfulness of antidepressants is associated with a general lack of exposure to depression, leading to an underestimation of its seriousness and of the necessity for intervention.

Introduction

Surveys of the public in a number of developed countries have found that negative attitudes towards psychiatric medications are common (Angermeyer et al., 1993, Fischer et al., 1999, Goldney et al., 2001, Jorm et al., 1997a, Jorm et al., 1997b, Jorm et al., 1997c, Priest et al., 1996). These beliefs contrast sharply with the positive views of most health professionals (Caldwell and Jorm, 2000, Jorm et al., 1997b). Despite some recent professional debate about the balance of risks and benefits with antidepressants (Fergusson et al., 2005, Gunnell and Ashby, 2004), public attitudes have become more positive over time (Angermeyer and Matschinger, 2004, Jorm et al., in press, Paykel et al., 1998). Nevertheless, there is still a big gap between public and professional thinking. This gap presents a challenge to the implementation of evidence-based treatment for depression because it may affect willingness to seek help and adherence to prescribed treatments. Patient attitudes towards antidepressants have also been found to have a major effect on the cost-effectiveness of treatment, with negative attitudes associated with a lack of cost-effectiveness (Pyne et al., 2005).

The purpose of this paper is to present data from an Australian national survey on factors associated with the belief that antidepressants are harmful. Better understanding of the factors associated with this belief may help in the design and targeting of campaigns to improve depression literacy in the population. The factors examined in the study covered sociodemographic characteristics, exposure to depression, ability to recognize depression, beliefs about other depression interventions, beliefs about long-term outcomes with and without treatment, beliefs about causes, and stigmatizing attitudes.

Section snippets

Survey methodology

The survey methodology has been described previously (Jorm et al., 2005a, Jorm et al., 2005b). A household survey was carried out of Australian adults aged 18 or over by the company AC Nielsen. The achieved sample was 3998 persons and the response rate was 34%.

Survey interview

The interview was based on the one used in an earlier Australian survey (Jorm et al., 1997a, Jorm et al., 1997c), but with additional questions. The survey questions centered on a vignette of a person with a mental disorder. On a random

Prevalence of beliefs about antidepressants

For the depression vignette, 46.7% thought antidepressants would be helpful and 27.5% harmful. For the depression/suicidal vignette, the respective frequencies were 52.5% and 23.4%. Because the findings on factors associated with antidepressant beliefs were similar for the two vignettes, only the data on the depression/suicidal vignette are presented below. This vignette presents a more severely affected person who is clearly in need of intervention, so negative beliefs represent a more extreme

Discussion

We found that around a quarter of Australian adults believe that antidepressants would be harmful for a person who is depressed and suicidal. For a case of this severity, some action is clearly needed, so this belief is of particular concern.

Examination of factors associated with this belief gives some insight into its origin. To some extent it simply reflects lack of knowledge about depression, as shown by the association with less education, less exposure to depression, and poorer recognition

Conclusion

What are the implications of these findings for changing public beliefs? The findings suggest that belief in the harmfulness of antidepressants is associated with a general lack of exposure to depression, leading to an underestimation of its seriousness and of the necessity for intervention. Consequently, public campaigns may not need to focus specifically on antidepressants. A better approach might be to increase public awareness of depression and reduce stigma through media exposure to people

Acknowledgments

This study is part of the Australia–Japan Partnership, which is an agreement between the governments of the two countries for joint projects in areas of health. Funding for the survey was provided by the Australian Department of Health and Ageing, a National Health and Medical Research Council Program Grant, and “beyondblue: the national depression initiative”. We thank Kelly Blewitt for her assistance with the survey.

References (19)

  • R.D. Goldney et al.

    Mental health literacy: an impediment to the optimum treatment of major depression in the community

    J. Affect. Disord.

    (2001)
  • M.C. Angermeyer et al.

    Public attitudes towards psychotropic drugs: have there been any changes in recent years?

    Pharmacopsychiatry

    (2004)
  • M.C. Angermeyer et al.

    Benefits and risks of psychotropic medication in the eyes of the general public: results of a survey in the Federal Republic of Germany

    Pharmacopsychiatry

    (1993)
  • O. Benkert et al.

    Public opinion on psychotropic drugs: an analysis of the factors influencing acceptance or rejection

    J. Nerv. Ment. Dis.

    (1997)
  • T.M. Caldwell et al.

    Mental health nurses' beliefs about interventions for schizophrenia and depression: a comparison with psychiatrists and the public

    Aust. N. Z. J. Psychiatry

    (2000)
  • D. Fergusson et al.

    Association between suicide attempts and selective serotonin reuptake inhibitors: systematic review of randomized controlled trials

    Br. Med. J.

    (2005)
  • W. Fischer et al.

    Determining factors and the effects of attitudes towards psychotropic medication

  • K.M. Griffiths et al.

    Effect of web-based depression literacy and cognitive-behavioural therapy interventions on stigmatising attitudes to depression: randomised controlled trial

    Br. J. Psychiatry

    (2004)
  • D. Gunnell et al.

    Antidepressants and suicide: what is the balance of benefit and harm

    Br. Med. J.

    (2004)
There are more references available in the full text version of this article.

Cited by (52)

  • A shared socio-economic pathway based framework for characterising future emissions of chemicals to the natural environment

    2022, Futures
    Citation Excerpt :

    High social cohesion (e.g. playing sport, social encounters) is associated with lower depressive symptoms and better mental health (Almedom, 2005; Wang et al., 2019). Exploratory review also showed that society divergence and malicious regards to the mental health issue discourage individuals to take antidepressants (Jorm et al., 2005; Lewer et al., 2015; Park et al., 2018). While impacts of social participation was not directly studied with respect to antidepressants, we considered that social participation and social cohesion are positively related.

  • Mental health literacy levels

    2018, Archives of Psychiatric Nursing
  • Beliefs about depression - Do affliction and treatment experience matter? Results of a population survey from Germany

    2014, Journal of Affective Disorders
    Citation Excerpt :

    In this study, being familiar with depression meant either respondents who had been in treatment for depression themselves or who had such a person among their family or friends (Holzinger et al., 2011). Other studies found that people with exposure to depression were less likely to believe that antidepressants are harmful (Jorm et al., 2005; Reavley and Jorm, 2012). Beliefs about the helpfulness of diverse medical, psychological and lifestyle interventions were studied by Jorm et al. (2000).

  • Depressed but not legally mentally impaired

    2014, International Journal of Law and Psychiatry
    Citation Excerpt :

    As such, affected individuals are perceived to be well able to discern right from wrong, and to control their conduct. Jorm, Christensen, and Griffiths (2005) and Jorm, Kitchener, Kanowski, and Kelly (2007) argue that the Australian public does not believe that medical treatment is necessary for conditions like depression, clearly illustrating how the seriousness of depressive illnesses is often underestimated. Depression is seen as a part of life, an aspect of ‘the human condition’ resulting from adverse life situations (Hogg, 2011, p. 654).

  • Belief in the harmfulness of antidepressants: Associated factors and change over 16 years

    2012, Journal of Affective Disorders
    Citation Excerpt :

    Similar associations between exposure to treatment and more positive beliefs have been seen in other surveys (Aikens et al., 2008; Dahlberg et al., 2008) Notably, in the 2011 survey, unlike the 2003/2004 survey (Jorm et al., 2005a); level of education was not associated with belief in harmfulness. Examination of changes over time showed that this lack of difference in 2011 was due to a greater fall in belief in harmfulness in those with a lower level of education than in those with a higher level of education.

View all citing articles on Scopus
View full text