Original scientific articleColon and Rectal Complications after Heart and Lung Transplantation
Section snippets
Patient selection
We retrospectively reviewed the medical records of all heart, lung, and heart-lung transplant recipients who required evaluation by a member of the Division of Colon and Rectal Surgery at the University of Minnesota between January 1, 1978, and November 15, 2004. Patients were included in the study if they required an opinion or intervention (endoscopic or surgical) by a CR surgeon on or after the date of transplantation. Events were classified as primarily CR or AR. Major complications were
Results
Between January 1, 1978 and November 15, 2004, 1,012 patients received thoracic transplantations (530 heart, 435 lung, and 47 heart-lung recipients). The ratio of men to women was approximately 2:1. Mean age at transplantation was 52.6 years (range 20 to 71 years). The most common disorder necessitating lung transplantation was obstructive lung disease. Heart transplantation was performed most often for ischemic cardiomyopathy. Heart-lung transplantations were performed for primary pulmonary
Discussion
Although CR and AR problems are common complications of abdominal solid organ transplantation, little is known about their incidence and severity in thoracic transplantation. Small studies focusing on complications of the lower GI tract have been performed in renal transplant recipients, and the incidence of colonic complications in these reports ranges from 7.4% to 8.6%.6, 7 A larger series following more than 2,000 renal transplant patients over 30 years found a 0.5% incidence of colonic
References (33)
- et al.
Gastrointestinal complications requiring surgical management in renal transplant recipients
Transplant Proc
(2002) - et al.
Colon perforation after lung transplantation
Ann Thoracic Surg
(1996) - et al.
Temporal changes in the management of diverticulitis
J Surg Res
(2005) - et al.
Severe diverticulitis after heart, lung, and heart-lung transplantation
J Heart Lung Transplant
(2004) - et al.
General surgical complications in heart and heart-lung transplantation
Surgery
(1985) - et al.
Major abdominal complications following cardiac transplantation
Arch Surg
(1989) - et al.
Gastrointestinal complications after cardiac transplantation
Ann Surg
(1990) - et al.
Gastrointestinal complications in heart and heart-lung transplant patients
J Heart Lung Transplant
(1991) - et al.
Gastrointestinal complications of renal transplantation. 2. The colon
Can Med Assoc J
(1978) - et al.
Colonic complications in renal transplant recipients
Dis Colon Rectum
(1988)
Acute colonic complications after kidney transplantation
Acta Chir Belg
The spectrum of colonic complications in a lung transplant population
Ann Transplant
Acute diverticulitis in heart- and lung transplant patients
Transplant Int
Acute diverticulitis in heart transplant recipients
Transplant Int
Sigmoid diverticular perforation complicating lung transplantation
J Heart Lung Transplant
Diverticular disease of the colon—on the risea study of hospital admissions in England between 1989/1990 and 1999/2000
Cited by (35)
Early Postoperative Outcomes of Lung Transplant Recipients With Abdominal Adverse Events
2023, Transplantation ProceedingsDiverticulitis occurs early after lung transplantation
2014, Journal of Surgical ResearchCitation Excerpt :In patients who developed diverticulitis, eight out of 14 (57%) underwent surgery with a mortality rate of 12.5%. This higher rate of surgical intervention, along with the high mortality rate, is both consistent with previous studies [1,4]. Six of the 14 patients (43%) who developed diverticulitis were successfully managed medically.
Early laparotomy after lung transplantation: Increased incidence for patients with α1-anti-trypsin deficiency
2014, Journal of Heart and Lung TransplantationSurgery in the Immunocompromised Patient
2012, Shackelford's Surgery of the Alimentary Tract: Volume 1-2, Seventh EditionIntermediate and Late Complications of Lung Transplantation
2010, Medical Management of the Thoracic Surgery PatientIntermediate and Late Complications of Lung Transplantation
2009, Medical Management of the Thoracic Surgery Patient
Competing Interests Declared: None.