Scientific articleCorrelation Between Distal Radial Cortical Thickness and Bone Mineral Density
Section snippets
Materials and Methods
After we obtained institutional review board approval, we analyzed a subset of data collected as part of a cross-sectional study of postmenopausal women with distal radius fractures conducted at 2 academic institutions. Between 2011 and 2013, DXA scans were obtained for 80 consecutive women over age 50 years who had sustained distal radius fractures. This group had a mean age of 66 years (range, 50–94 y); 81% were Caucasian, 9% were black, 8% were Hispanic, and 2% were classified as other
Results
For the entire cohort, mean femoral bone density was 0.84 ± 0.14 g/cm2 and mean lumbar spine density was 1.00 ± 0.15 g/cm2. For cortical thickness measures, mean CBT was 5.75 ± 1.07 mm and mean GT1 and GT2 were 0.40 ± 0.08 and 0.42 ± 0.08, respectively.
Analysis using linear regression showed that BCT (r = 0.39; P < .01), distal GT1 (r = 0.44; P < .01), and average GT2 (r = 0.44; P < .01) were moderately associated with femoral bone density values (Fig. 2). Conversely, BCT (r = –0.05; P = .7), GT
Discussion
This study demonstrated that cortical bone density measured on standard PA wrist radiographs correlated with femoral bone mineral density on DXA. Patients with a diagnosis of osteoporosis based on DXA had a significantly thinner BCT, which supports the correlation between cortical thickness and bone density. Bicortical thickness of the proximal humerus and hand has been previously correlated with osteoporosis as detected by DXA7, 14 and has been suggested as a screening tool to determine which
Acknowledgments
Funding for this work was received from the American Foundation for Surgery of the Hand and the Orthopaedic Research and Education Foundation (RJOS/DePuy/OREF grant). The authors acknowledge the assistance of Katy Coyle, RN, Mark Cote, PhD, Lindsay Herder, BS, and Mary Bouxsein, PhD.
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