Original articlePrevalence of Congenital Heart Defects in Metropolitan Atlanta, 1998-2005
Section snippets
Methods
MACDP is a population-based surveillance system for major structural birth defects, chromosomal abnormalities, and clinical syndromes established in 1967 by the Centers for Disease Control and Prevention (CDC), Emory University, and the Georgia Mental Health Institute.8 Since that time, the program has conducted surveillance for birth defects among liveborn and stillborn infants greater than or equal to 20 weeks' gestation born to residents of the 5 central counties of metropolitan Atlanta
Results
During 1998 to 2005, there were 3240 infants identified with CHD and 398 140 live births in metropolitan Atlanta. The overall prevalence of CHD was 81.4 infants/10 000 births, and the prevalence of critical CHD was 15.6 infants/10 000 births (Table II). Because some infants had more than 1 independent CHD, the sum of individual CHD prevalence is greater than the total CHD prevalence.
The left-to-right shunt lesions were the most prevalent group of defects, comprising more than half of the total
Discussion
Our study provides prevalence estimates for several CHD that were not previously discussed in the Hoffman and Kaplan4 review (Table II), including subtypes of septal defects and rare defects such as discordant atrioventricular connections (congenitally corrected TGA), heterotaxy syndrome, and interrupted aortic arch type B, using the STS nomenclature and classification system. The most common defects were muscular VSD, perimembranous VSD, and secundum ASD with prevalence estimates of 27.5,
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Cited by (0)
Supported by National Institute of Environmental Health Sciences (NIEHS) grant R01-ES012967-01A1.
The findings and conclusions in this report are those of the authors and do not necessarily represent the views of the Centers for Disease Control and Prevention. The authors declare no potential conflicts of interest.