The central role of IL-33/IL-1RL1 pathway in asthma: From pathogenesis to intervention
Under a Creative Commons license
open access
Keywords
Asthma
IL-1RL1
IL-33
Immune cells
Epithelial cells
Genetics
Pharmacotherapy
Abbreviations
A disintegrin and metalloproteinase domain-containing protein 33
ADAM33
Activator protein-1
AP-1
Airway Hyperresponsiveness
AHR
Airway Smooth Muscle Cells
ASMCs
Alternaria alternata
ALT
Amphiregulin
AREG
Atopic dermatitis
AD
Bronchoalveolar lavage fluid
BALF
c-Jun N-terminal kinase
JNK
Carcinoma Cell Line
CCL
Damage Associated Molecular Pattern
DAMP
Dendritic cells
DCs
Early-Associated-Response
EAR
Expression quantitative trait loci
eQTL
Extracellular Receptor Kinase
ERK
Forced Expiratory Volume in one second
FEV1
GATA Binding Protein 1
GATA 1
Genome-Wide Association Study
GWAS
Granulocyte-macrophage colony-stimulating factor
GM-CSF
Histone 2A - Histone 2B
H2A-H2B
Histone-lysine N-methyltransferase
SUV39H1
IKappaB Kinase
IĸB
Immunoglobulin E
IgE
Inhaled Corticosteroids
ICS
Interferon gamma
INFγ
Interleukin 1 receptor accessory protein
IL-1RAcP
Interleukin 1 Receptor Like 1
IL-1RL1
Interleukin - 33
IL-33
Interleukin -
IL-
Interleukin receptor associated kinases
IRAK1/4
Invariant natural killer T
iNKT
Janus Kinase pathway
JAK
Late-Associated-Response
LAR
Linkage Disequilibrium
LD
Long-acting beta-adrenoceptor agonist
LABA
Major histocompatibility complex
MHC
mammalian target of rapamycin
mTOR
Mast cells
MCs
MyD88-adapter-like
MAL1
Myeloid differentiation primary response 88
MyD88
N-acetylglucosamine
NAG
Natural Killer cells
NKs
NLR family pyrin domain containing 3 - nucleotide-binding oligomerization domain
NLRP3-NOD
Nuclear Factor Kappa-light-chain-enhancer of activated B cells
NF-κB
Nuclear Factor-High Endothelial Venules
NF-HEV
phosphoinositide 3-kinase
PI3k
Protein quantitative trait loci
pQTL
Regulatory T cells
Treg
Reticular Basement Membrane
RBM
Short-acting beta-adrenoceptor agonist
SABA
Signal Transducer And Activator Of Transcription 5A
STAT5A
Single Ig IL-1-related receptor
SIGIRR
Single nucleotide polymorphisms
SNP
Stem cells antigen-1
Sca-1
T helper 2 lymphocyte
Th2
T helper 17 cells
Th17
T-cell receptor
TCR
The Toll/interleukin-1 receptor
TIR
Thymic stromal lymphopoietin
TSLP
Toll/Interleukin-1 receptor 8
TIR8
TRAF6
Tumor necrosis factor receptor (TNFR)-associated factor 6, TRAF6
Tumour Necrosis Factor alpha
TNF-α
Type 2 innate lymphoid cells
ILC2
Type 2
T2
Cited by (0)
© 2021 The Authors. Published by Elsevier Inc.