Expedient asymmetric synthesis of a functionalized 5-7-6 fused tricyclic skeleton present in caribenol A through ring opening-ring closing metathesis of a norbornene derivative
Graphical abstract
A concise synthesis of the tricyclic core structure present in highly biologically active terpenoids caribenol A is described using RO-RCM of a norbornene derivative.
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Acknowledgements
Financial support from the Department of Science and Technology, Government of India through Ramanna Fellowship to S.G. is gratefully acknowledged. S.M. thanks CSIR, New Delhi for a senior research fellowship.
References and notes (9)
- et al.
Tetrahedron Lett.
(1997)et al.Synlett
(1997) - et al.
J. Org. Chem.
(2007) - et al.
Science
(1992) - et al.
Eur. J. Org. Chem.
(2003)et al.Chem. Asian J.
(2007)et al.J. Org. Chem.
(1990)et al.Angew. Chem., Int. Ed.
(1997)et al.Synlett
(1998)et al.J. Am. Chem. Soc.
(2000)et al.Tetrahedron
(2002)et al.J. Am. Chem. Soc.
(2006)et al.Tetrahedron Lett.
(2006)
There are more references available in the full text version of this article.
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