11th Congress of the Andalusian Society of Organ and Tissue TransplantationLiver transplantationLiver Retransplantation: The Changing Scenario in a Tertiary Medical Center
Section snippets
Materials and Methods
We performed a single-center observational, retrospective study including patients who underwent LRT in a tertiary medical center between January 2002 and December 2018. LRTs were classified as early (within the first 6 months after primary transplant) or late (after 6 months). In terms of data analysis, qualitative variables are expressed as frequencies and absolute numbers, and quantitative variables as median and interquartile range. We collected recipient variables such as age, sex, body
Results
During the period under review a total of 468 transplants were made. Thirty-two of them (6.8%) underwent an LRT. Demographics and characteristics of patients are described in Table 1. The indications of LRT were: 8 HAT with ischemic cholangiopathy (IC) (25%), 7 CR (21.8%), 6 nonarterial IC (18.7%), 4 EGF (12.5%), 1 (3.1%) HCV reinfection, 1 (3.1%) portal thrombosis, and 5 nonregistered causes. The 35.2% of patients met Olthoff criteria and the median MEAF score was 4.46 (2.35-6.57). Vascular
Discussion
In this review of the practice of a low to medium volume LT unit, we have obtained an LRT rate of 6.8%, of which the most common indication was HAT with IC. The most frequent and severe postoperative morbidity made reference to vascular complications, mostly with the development of HAT.
In recent years, LT rate has showed a global rise, due to the increase of available grafts and some new indications under scrutiny. Because of that, LRT indications have became an issue of debate among experts.
Conclusion
A low to medium volume LT unit can obtain LRT rates aligned with current standards. In our experience, the most common cause of LRT was HAT causing IC, followed by CR. Because of that, a narrow and long-term follow-up and an early detection and treatment of these complications are mandatory.
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