Data and code availability
The all-biobank and ancestry-specific GWAS summary statistics are publicly available for downloading at https://www.globalbiobankmeta.org/resources and browsed at the PheWeb Browser http://results.globalbiobankmeta.org/. The PRS weights re-estimated using PRC-CS-auto for multi-ancestry GWAS including all biobanks and leave-UKBB-out multi-ancestry GWAS have been uploaded to PGS Catalog (https://www.pgscatalog.org/) under the study ID PGP000262. 1000 Genome Phase 3 data can be accessed at NCBI FTP site: ftp://ftp-trace.ncbi.nih.gov/1000genomes/ftp. We used UKB data via application 31063. The software used in this study can be found at: Plink (https://www.cog-genomics.org/plink/), PRS-CS (https://github.com/getian107/PRScs), and SBayesS/GCTB (https://cnsgenomics.com/software/gctb/). The codes used in this study have been deposited to Zenodo: https://doi.org/10.5281/zenodo.7321467. Any additional information required to reanalyze the data reported in this paper is available from the lead contact upon request.