Elsevier

Genomics

Volume 100, Issue 1, July 2012, Pages 8-13
Genomics

EXP-PAC: Providing comparative analysis and storage of next generation gene expression data

https://doi.org/10.1016/j.ygeno.2012.05.007Get rights and content
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Abstract

Microarrays and more recently RNA sequencing has led to an increase in available gene expression data. How to manage and store this data is becoming a key issue. In response we have developed EXP-PAC, a web based software package for storage, management and analysis of gene expression and sequence data. Unique to this package is SQL based querying of gene expression data sets, distributed normalization of raw gene expression data and analysis of gene expression data across experiments and species. This package has been populated with lactation data in the international milk genomic consortium web portal (http://milkgenomics.org/). Source code is also available which can be hosted on a Windows, Linux or Mac APACHE server connected to a private or public network (http://mamsap.it.deakin.edu.au/~pcc/Release/EXP_PAC.html)

Highlights

► EXP-PAC stores and analyzes sequence and expression data through a web portal. ► EXP-PAC supports comparison of genes across experimental platforms and species. ► We provide a comprehensive database of lactation gene expression data. ► We investigate the genetic difference between the sow and mouse lactation process.

Keywords

Microarray
Gene expression
Comparative analysis
Database

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