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Absence of shock-like reactions to ivermectin in dogs infected with Dirofilaria immitis

Published online by Cambridge University Press:  05 June 2009

P. F. L. Boreham  and
R. B. Atwell
P. F. L. Boreham
Affiliation:
Queensland Institute of Medical Research, Bramston Terrace, Herston, Brisbane, 4006, Australia;
R. B. Atwell
Affiliation:
Department of Veterinary Medicine, University of Queensland, St. Lucia, Brisbane, 4067, Australia
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Abstract

Six dogs infected with Dirofilaria immitis and known to develop shock-like reactions after administration of diethylcarbamazine (DEC) were given ivermectin 50μg/kg orally. None of the dogs showed any adverse reaction and subsequently all reacted to DEC 20mg/kg orally.

Type
Research Papers
Information
Journal of Helminthology , Volume 57 , Issue 3 , September 1983 , pp. 279 - 281
Copyright
Copyright © Cambridge University Press 1983

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References

REFERENCES

Awadzi, K. (1980) The chemotherapy of onchocerciasis II. Quantitation of the clinical reaction to microfilaricides. Annals of Tropical Medicine and Parasitology. 74, 189–197.CrossRefGoogle ScholarPubMed
Campbell, W. C. & Blair, L. S. (1978) Efficacy of Avermectins against Dirofilaria immitis in dogs. Journal of Helminthology, 52, 308–310.CrossRefGoogle ScholarPubMed
Egerton, J. R., Birnbaum, J., Blair, L. S., Chabala, J. C., Conroy, J., Fisher, M. H., Mrozik, H., Ostlind, D. A., Wilkins, C. A. & Campbell, W. C. (1980) 22, 23-dihydroavermectin B1, a new broad-spectrum antiparsitic agent. British Veterinary Journal, 136, 88–97.CrossRefGoogle Scholar
Henson, P. M., Mackenzie, C. D. & Spector, W. G. (1979) Inflammatory reactions in onchocerciasis: a report on current knowledge and recommendations for further study. Bulletin of the World Health Organization, 57, 667–682.Google Scholar
Mak, J. W. & Zaman, V. (1980) Drug trials with levamisole hydrochloride and diethylcarbamazine in Bancroftian and Malayan filariasis. Transactions of the Royal Society of Tropical Medicine and Hygiene. 74, 285–291.Google Scholar