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Helminth detoxification mechanisms

Published online by Cambridge University Press:  05 June 2009

J. Barrett
J. Barrett
Affiliation:
Institute of Biological Sciences, University of Wales, Aberystwyth, Ceredigion, SY23 3DA, UK
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Extract

Detoxification mechanisms in parasitic helminths have not been extensively studied, despite their obvious relevance to drug development and drug resistance. Differences in detoxification enzymes between the parasite and its host may be exploitable in the design of pro-drugs, whilst selective inhibition of the parasites protective enzymes could increase their sensitivity to drug action and also make them more susceptible to the host's defence mechanisms.

Type
Symposium Papers
Information
Journal of Helminthology , Volume 71 , Issue 2 , June 1997 , pp. 85 - 90
Copyright
Copyright © Cambridge University Press 1997

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