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Seroprevalence of toxocariasis in hypereosinophilic individuals in Ahwaz, south-western Iran

Published online by Cambridge University Press:  07 July 2011

S. Maraghi ,
A. Rafiei ,
R. Hajihossein  and
S. M. Sadjjadi
S. Maraghi
Affiliation:
Department of Parasitology and Mycology, Tropical Disease Research Center, Thalassemia and Haemoglobinopathy Research Center, Jundishapur University of Medical Sciences, Ahwaz, Iran
A. Rafiei
Affiliation:
Department of Parasitology and Mycology, Tropical Disease Research Center, Thalassemia and Haemoglobinopathy Research Center, Jundishapur University of Medical Sciences, Ahwaz, Iran
R. Hajihossein
Affiliation:
Department of Parasitology and Mycology, Tropical Disease Research Center, Thalassemia and Haemoglobinopathy Research Center, Jundishapur University of Medical Sciences, Ahwaz, Iran
S. M. Sadjjadi*
Affiliation:
Department of Parasitology and Mycology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran
*
*Fax: +987112305291 E-mail: smsadjjadi@sums.ac.ir
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Abstract

Eosinophilia in human peripheral blood is caused by different agents, including toxocariasis. The present study aimed to evaluate the prevalence of toxocariasis in hypereosinophilic individuals in the city of Ahwaz, located in south-western Iran, using enzyme-linked immunosorbent assay and Western blot techniques. Serum samples were examined from 100 individuals with peripheral blood eosinophilia and also from another 100 individuals without eosinophilia as the control group. In hypereosinophilic individuals seroprevalence antibodies against Toxocara were found in 19 (19%), of whom 12 (63.15%) were female and 7 (36.85%) were male. Positive sera were subsequently confirmed by Western blot. All of the observed bands ranged from 24 to 100 kDa. Antibodies against Toxocara were found in 1% of the control group, but were not confirmed by Western blot. The results showed significant differences between the frequency of infection within age and gender (P < 0.05); the highest prevalence of infection was observed in adults. Differences between the hypereosinophilic and healthy individuals, in terms of Toxocara infection frequency, also proved significant (P < 0.05).The present study thus confirmed the significant prevalence of toxocariasis as a hygienic problem among hypereosinophilic individuals in this area. It is, therefore, necessary to examine these individuals for toxocariasis.

Type
Research Papers
Information
Journal of Helminthology , Volume 86 , Issue 2 , June 2012 , pp. 241 - 244
Copyright
Copyright © Cambridge University Press 2011

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