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A study of acetylcholinesterase throughout the life cycle of Nippostrongylus brasiliensis

Published online by Cambridge University Press:  06 April 2009

Barbara E. Sanderson  and
Bridget M. Ogilvie
Barbara E. Sanderson
Affiliation:
The Research Laboratories, May and Baker Ltd, Dagenham, Essex and National Institute for Medical Research, Mill Hill, London, N. W. 7
Bridget M. Ogilvie
Affiliation:
The Research Laboratories, May and Baker Ltd, Dagenham, Essex and National Institute for Medical Research, Mill Hill, London, N. W. 7
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Extract

Acetylcholinesterase activity, measured per unit wet weight, is relatively low in the eggs and infective larvae of N. brasiliensis. It increases rapidly during the parasitic phase, especially in the late 3rd- and early 4th-larval stages. Activity in normal adults is extremely high (× 15 egg activity) and this is doubled again in immune-damaged adults. Possible functions of N. brasiliensis acetylcholinesterase are discussed.

It is a pleasure to acknowledge the technical assistance of Miss Anne Cronin and Miss Beryl Crooks.

Type
Research Article
Information
Parasitology , Volume 62 , Issue 3 , June 1971 , pp. 367 - 373
Copyright
Copyright © Cambridge University Press 1971

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