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Experimental infections of pigs and mice with selected genotypes of Ascaris

Published online by Cambridge University Press:  11 July 2006

W. PENG ,
K. YUAN ,
M. HU ,
G. PENG ,
X. ZHOU ,
N. HU  and
R. B. GASSER
W. PENG
Affiliation:
Jiangxi Medical Science Research Institute, Nanchang University, 461 Ba Yi Road, Nanchang, Jiangxi 330006, People's Republic of China Department of Veterinary Science, The University of Melbourne, 250 Princes Highway, Werribee, Victoria 3030, Australia
K. YUAN
Affiliation:
Jiangxi Medical Science Research Institute, Nanchang University, 461 Ba Yi Road, Nanchang, Jiangxi 330006, People's Republic of China
M. HU
Affiliation:
Department of Veterinary Science, The University of Melbourne, 250 Princes Highway, Werribee, Victoria 3030, Australia
G. PENG
Affiliation:
Nanchang Municipal Centre for Disease Control and Prevention, Nanchang 330006, People's Republic of China
X. ZHOU
Affiliation:
Department of Parasitology, College of Basic Medicine, Nanchang University, 603 Ba Yi Road, Nanchang, Jiangxi 330006, People's Republic of China
N. HU
Affiliation:
Department of Parasitology, College of Basic Medicine, Nanchang University, 603 Ba Yi Road, Nanchang, Jiangxi 330006, People's Republic of China
R. B. GASSER
Affiliation:
Department of Veterinary Science, The University of Melbourne, 250 Princes Highway, Werribee, Victoria 3030, Australia
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Abstract

Extending a previous investigation of the genotypic variability within Ascaris from humans and pigs, experimental infections of mice and pigs with selected genotypes of Ascaris were performed in the present study to explore possible host affiliation. Initial findings indicate that there is a significant difference in the ability of Ascaris eggs of genotype G1 (derived from human) and G3 (derived from pig) to infect and establish as larvae in mice and as adults in pigs, supporting the difference in the frequencies of the genotypes reported previously in natural Ascaris populations in pigs and humans in areas in China endemic for ascariasis.

Keywords

AscarisChinahost affiliationgenotypesexperimental infectionspigsmice
Type
Research Article
Information
Parasitology , Volume 133 , Issue 5 , November 2006 , pp. 651 - 657
Copyright
2006 Cambridge University Press

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