Hostname: page-component-848d4c4894-m9kch Total loading time: 0 Render date: 2024-05-05T09:44:22.726Z Has data issue: false hasContentIssue false

Randomized Controlled Trial of Yogic Meditation Techniques for Patients With Obsessive-Compulsive Disorder

Published online by Cambridge University Press:  07 November 2014

Abstract

The objective of this study was to compare efficacy of two meditation protocols for treating patients with obsessive-compulsive disorder (OCD). Patients were randomized to two groups—matched for sex, age, and medication status—and blinded to the comparison protocol. They were told the trial would last for 12 months, unless one protocol proved to be more efficacious. If so, groups would merge, and the group that received the less efficacious treatment would also be afforded 12 months of the more effective one. The study was conducted at Children's Hospital, San Diego, Calif. Patients were selected according to Diagnostic and Statistical Manual of Mental Disorders, Third Edition-Revised (DSM-III-R) criteria and recruited by advertisements and referral. At baseline, Group 1 included 11 adults and 1 adolescent, and Group 2 included 10 adults. Group 1 employed a kundalini yoga meditation protocol and Group 2 employed the Relaxation Response plus Mindfulness Meditation technique. Baseline and 3-month interval testing was conducted using the Yale-Brown Obsessive Compulsive Scale (Y-BOCS), Symptoms Checklist-90-Revised Obsessive Compulsive (SCL-90-R OC) and Global Severity Index (SCL-90-R GSI) scales, Profile of Moods scale (POMS), Perceived Stress Scale (PSS), and Purpose in Life (PIL) test. Seven adults in each group completed 3 months of therapy. At 3 months, Group 1 demonstrated greater improvements (Student's independent groups t-test) on the Y-BOCS, SCL-90-R OC and GSI scales, and POMS, and greater but nonsignificant improvements on the PSS and PIL test. An intent-to-treat analysis (Y-BOCS) for the baseline and 3-month tests showed that only Group 1 improved. Within-group statistics (Students paired t-tests) showed that Group 1 significantly improved on all six scales, but Group 2 had no improvements. Groups were merged for an additional year using Group 1 techniques. At 15 months, the final group (N=11) improved 71%, 62%, 66%, 74%, 39%, and 23%, respectively, on the Y-BOCS, SCL-90-R OC SCL-90-R GSI, POMS, PSS, and PIL; P<0.003 (analysis of variance). This study demonstrates that kundalini yoga techniques are effective in the treatment of OCD.

Type
Feature Articles—Original Research
Copyright
Copyright © Cambridge University Press 1999

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

REFERENCES

1.Rapoport, JL. The waking nightmare: an overview of obsessive compulsive disorder. J Clin Psychiatry. 1990;51:2528.Google ScholarPubMed
2.Rasmussen, SA, Eisen, JL. Epidemiology of obsessive compulsive disorder. J Clin Psychiatry. 1990;51:1013.Google ScholarPubMed
3.Jenike, MA. Psychotherapy of the patient with obsessive compulsive personality disorder. In: Jenike, MA, Baer, L, Minichiello, WE, eds. Obsessive-Compulsive Disorders: Theory and Management, St Louis, Mo: Mosby Year Book; 1990.Google Scholar
4.Goodman, WK, McDougle, CJ, Price, LH. Pharmacotherapy of obsessive compulsive disorder. J Clin Psychiatry. 1992;53:2937.Google ScholarPubMed
5.Jenike, MA. Pharmacologic treatment of obsessive compulsive disorders. Psychiatr Clin North Am. 1992;15:895919.CrossRefGoogle ScholarPubMed
6.Goodman, WK. Price, LH, Rasmussen, SA, et al.The Yale-Brown Obsessive Compulsive Scale. Arch Gen Psychiatry. 1989;46:10061011.CrossRefGoogle ScholarPubMed
7.Goodman, WK, McDougle, CJ, Barr, LC, Aronson, SC, Price, LH. Biological approaches to treatment-resistant obsessive compulsive disorder. J Clin Psychiatry. 1993;54:1626.Google ScholarPubMed
8.Pato, MT, Zohar-Kadouch, R, Zohar, J, Murphy, DL. Return of symptoms after discontinuation of clomipramine in patients with obsessive-compulsive disorder. Am J Psychiatry. 1988;145:15211525.Google ScholarPubMed
9.Leonard, HL, et al.A double-blind substitution during long-term clomipramine treatment in children and adolescents. Arch Gen Psychiatry. 1991;48:922927.CrossRefGoogle ScholarPubMed
10.Fontaine, R, Chouinard, G. Fluoxetine in the long-term treatment of obsessive compulsive disorder. Psychiatr Ann. 1989;19:8891.CrossRefGoogle Scholar
11.Kobak, KA, Griest, JH, Jefferson, JW, Katzelnick, DJ, Henk, HJ. Behavioral versus pharmacological treatments of obsessive compulsive disorder: a meta-analysis. Psychopharmacology. 1998;136:205216.CrossRefGoogle ScholarPubMed
12.O'Sullivan, G, Noshirvani, H, Marks, I, Monleiro, W, Lelliott, P. Six-year follow-up after exposure and clomipramine therapy for obsessive compulsive disorder. J Clin Psychiatry. 1991;52:150155.Google ScholarPubMed
13.Marks, IM. Review of behavioral psychotherapy. Am J Psychiatry. 1981;138:584592.Google ScholarPubMed
14.Shannahoff-Khalsa, DS, Beckett, LR. Clinical case report: efficacy of yogic techniques in the treatment of obsessive compulsive disorder. Int J Neurosci. 1996;85:117.CrossRefGoogle Scholar
15.Derogatis, LR. Symptom Checklist-90-Revised. Minneapolis, Minn: National Computer Systems; 1993.Google Scholar
16.Shannahoff-Khalsa, DS. Yogic meditation techniques are effective in the treatment of obsessive compulsive disorders. In: Hollander, E, Stein, D, eds. Obsessive Compulsive Disorders: Etiology, Diagnosis, and Treatment. New York, NY: Marcel Dekker; 1997:283329.Google Scholar
17.Diagnostic and Statistical Manual of Mental Disorders. 3rd ed rev. Washington, DC: American Psychiatric Association; 1987.Google Scholar
18.Shannahoff-Khalsa, DS. Stress technology medicine: a new paradigm for stress and considerations for self-regulation. In: Brown, MR, Koob, G, Rivier, C, eds. Stress: Neurobiology and Neuroendocrinology. New York, NY: Marcel Dekker; 1991:647679.Google Scholar
19.Benson, H. The Relaxation Response. New York, NY: Morrow; 1975.Google ScholarPubMed
20.Kabat-Zinn, J. An outpatient program in behavioral medicine for chronic pain patients based on the practice of mindfulness meditation: theoretical considerations and preliminary results. Gen Hosp Psychiatry. 1982;4:3747.CrossRefGoogle ScholarPubMed
21.Kabat-Zinn, J. Full Catastrophe Living: Using the Wisdom of Your Body and Mind to Face Stress, Pain, and Illness. New York, NY: Delacorte Press; 1990.Google Scholar
22.Kobak, KA, Greist, JH, Jefferson, JW, Katzelnick, DJ. Computer-administered clinical rating scales: a review. Psychopharmacology. 1996;127:291301.CrossRefGoogle ScholarPubMed
23.McNair, DM, Lorr, M, Droppleman, LF. Profile of Moods Scale. San Diego, Calif: Educational and Industrial Testing Service; 1971.Google Scholar
24.Cohen, S, Kamarck, T, Mermelstein, R. A global measure of perceived stress: Perceived Stress Scale. The Journal of Health and Human Behavior. 1983;24:386396.Google Scholar
25.Crumbaugh, JC, Maholick, LT. Purpose in Life Test, Test 168, Form A. Murfreesboro, Tenn: Psychometric Affiliates; 1976.Google Scholar
26.Woody, SR, Steketee, G, Chambless, DL. Reliability and validity of the Yale-Brown Obsessive-Compulsive Scale. Behav Res Ther. 1995;33:597605.CrossRefGoogle ScholarPubMed
27.Woody, SR, Steketee, G, Chambless, DL. The usefulness of the obsessive-compulsive scale of the Symptom Checklist-90-Revised. Behav Res Ther. 1995;33:607611.CrossRefGoogle ScholarPubMed
28.Werntz, DA, Bickford, RG, Shannahoff-Khalsa, DS. Selective hemispheric stimulation by unilateral forced nostril breathing. Human Neurobiology. 1987;6:165171.Google ScholarPubMed
29.Shannahoff-Khalsa, DS, Boyle, MR, Buebel, M. The effects of unilateral forced nostril breathing on cognition. Int J Neurosci. 1991;57:239249.CrossRefGoogle ScholarPubMed
30.Jella, SA, Shannahoff-Khalsa, DS. The effects of unilateral forced nostril breathing on cognitive performance. Int J Neurosci. 1993;73:6168.CrossRefGoogle ScholarPubMed
31.Schiff, BB, Rump, SA. Asymmetrical hemispheric activation and emotion: the effects of unilateral forced nostril breathing. Brain and Cognition. 1995;29:217231.CrossRefGoogle ScholarPubMed
32.Breiter, HC, Rauch, SL, Kwong, KK, et al.Functional magnetic resonance imaging of symptom provocation in obsessive-compulsive disorder. Arch Gen Psychiatry. 1996;53:595606.CrossRefGoogle ScholarPubMed
33.Goodman, WK, Kozak, MJ, Liebowitz, M, White, KL. Treatment of obsessive-compulsive disorder with fluvoxamine: a multicenter, double-blind, placebo-controlled trial. Int Clin Psychopharmacol. 1996;11:2129.CrossRefGoogle Scholar
34.Griest, JH, Jefferson, JW, Rosenfeld, R, Gutzmann, LD, March, JS, Barklage, NE. Clomipramine and obsessive-compulsive disorder: a placebo-controlled double-blind study of 32 patients. J Clin Psychiatry. 1990;51:292297.Google Scholar
35.Griest, JH, Jefferson, JW, Kobak, KA, Katzelnick, DJ, Serlin, RC. Efficacy and tolerability of serotonin transport inhibitors in obsessive-compulsive disorder. Arch Gen Psychiatry. 1995;52:5360.CrossRefGoogle Scholar
36.Marks, IM. Review of behavioral psychotherapy. Am J Psychiatry. 1981;138:584592.Google ScholarPubMed
37.Baer, L. Getting Control: Overcoming Your Obsessions and Compulsions. Boston, Mass: Little, Brown & Co; 1991.Google Scholar
38.Cottraux, J. Behavioral psychotherapy for obsessive compulsive disorder. International Review of Psychiatry. 1989;1:227234.CrossRefGoogle Scholar
39.Baer, L, Minichiello, WE. Behavior therapy for obsessive compulsive disorder. In: Jenike, MA, Baer, L, Minichiello, WE, eds. Obsessive-Compulsive Disorders: Theory and Management. St Louis, Mo: Mosby Year Book; 1990.Google Scholar