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Prospective Memory Deficits are Associated with Poorer Everyday Functioning in Parkinson's Disease

Published online by Cambridge University Press:  30 July 2012

Eva Pirogovsky ,
Steven Paul Woods ,
J. Vincent Filoteo  and
Paul E. Gilbert
Eva Pirogovsky
Affiliation:
San Diego State University – University of California San Diego Joint Doctoral Program in Clinical Psychology, San Diego, California
Steven Paul Woods
Affiliation:
Department of Psychiatry, University of California San Diego, San Diego, California
J. Vincent Filoteo
Affiliation:
Department of Psychiatry, University of California San Diego, San Diego, California Veterans Affairs, San Diego Health Care System, San Diego, California
Paul E. Gilbert*
Affiliation:
Department of Psychology, San Diego State University, San Diego, California
*
Correspondence and reprint requests to: Paul Gilbert, SDSU-UCSD Joint Doctoral Program in Clinical Psychology, 6363 Alvarado Court, Suite 103, San Diego, CA 92120. E-mail: pgilbert@sciences.sdsu.edu
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Abstract

Although individuals with Parkinson's disease (PD) evidence moderate deficits in prospective memory (PM), it is not known whether PM deficits confer an increased risk of poorer everyday functioning. In the current study, 33 individuals with PD and 26 demographically similar normal controls (NC) were administered performance-based and self-report measures of PM and everyday functioning, including medication and financial management. As compared to NC, PD participants demonstrated significantly lower scores on performance-based measures of PM and financial capacity, worse performance at a trend level on performance-based medication management and endorsed significantly greater self-reported declines in PM and instrumental activities of daily living (iADLs). In the PD sample, the laboratory measure of PM significantly correlated with performance-based measures of financial capacity and medication management and a self-report measure of medication management. Self-reported PM failures significantly correlated with perceived declines in iADLs, worse medication management, and poorer health-related quality of life. Although future studies are needed to examine the incremental ecological validity of PM in PD, findings from this study extend prior research by providing preliminary evidence that PM impairment may play a significant role in a range of critical everyday functions in PD. (JINS, 2012, 18, 1–10)

Keywords

NeuropsychologyExecutive functionMovement disordersActivities of daily livingMedication adherenceDementia
Type
Research Articles
Information
Journal of the International Neuropsychological Society , Volume 18 , Issue 6 , November 2012 , pp. 986 - 995
Copyright
Copyright © The International Neuropsychological Society 2012

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