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Attention-Deficit/Hyperactivity Disorder: A Historical Neuropsychological Perspective

Published online by Cambridge University Press:  04 December 2017

E. Mark Mahone*
Affiliation:
Kennedy Krieger Institute, Baltimore, Maryland Johns Hopkins University School of Medicine, Baltimore, Maryland
Martha B. Denckla
Affiliation:
Kennedy Krieger Institute, Baltimore, Maryland Johns Hopkins University School of Medicine, Baltimore, Maryland
*
Correspondence and reprint requests to: E. Mark Mahone, Department of Neuropsychology, Kennedy Krieger Institute, 1750 E. Fairmount Avenue, Baltimore, MD 21231. E-mail: mahone@kennedykrieger.org

Abstract

The behavior patterns of hyperactivity, impulsivity and inattention that would ultimately become recognized as Attention-Deficit Hyperactivity Disorder (ADHD) have been described for centuries. Nevertheless, in the past 35 years, advances in diagnostic methods, identification of biomarkers, and treatments have advanced at an exponential rate. ADHD is now recognized as the most common behavioral disorder of childhood, with risks extending well into adulthood for both males and females, leading to its identification as a significant public health issue. This historical neuropsychological review of ADHD emphasizes scientific highlights in the past 35 years related to ADHD, including the evolution of the diagnosis (from Hyperkinetic Reaction of Childhood to ADHD), influential theories (executive functions, cognitive-energetic, delay aversion), landmark treatment studies (Multimodal Treatment of ADHD [MTA] and Preschool ADHD Treatment Study [PATS]), and advances in brain mapping techniques (anatomic, functional, and resting state magnetic resonance imaging, diffusion tensor imaging). The review concludes by highlighting the challenges of studying and treating a heterogeneous neurodevelopmental disorder like ADHD, with emphasis on associated disorders and conditions (learning disabilities, sluggish cognitive tempo), special populations (girls, preschoolers, adults), and recommendations for scientific inquiry in the next 35 years. Neuropsychologists are well positioned to address the clinical and research challenges of the next generation of studies, especially involving advances in understanding the sexual dimor.phism, full developmental course, and dynamic risks associated with ADHD. (JINS, 2017, 23, 916–929)

Type
Section 4 – Pediatric Disorders
Copyright
Copyright © The International Neuropsychological Society 2017 

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References

REFERENCES

Abikoff, H.B., Vitiello, B., Riddle, M.A., Cunningham, C., Greenhill, L.L., Swanson, J.M., & Wigal, T. (2007). Methylphenidate effects on functional outcomes in the preschoolers with attention-deficit hyperactivity disorder treatment study (PATS). Journal of Child and Adolescent Psychopharmacology, 17, 581592. doi: 10.1089/cap.2007.0068 CrossRefGoogle ScholarPubMed
Agnew-Blais, J.C., Polanczyk, G.V., Danese, A., Wertz, J., Moffitt, T.E., & Arseneault, L. (2016). Evaluation of the persistence, remission, and emergence of attention-deficit/hyperactivity disorder in young adulthood. JAMA Psychiatry, 73, 713720.Google Scholar
American Academy of Pediatrics (2011). ADHD: Clinical practice guideline for the diagnosis, evaluation, and treatment of attention-deficit/hyperactivity disorder in children and adolescents. Pediatrics, 128(5), 116. doi: 10.1542/peds.2011-2654 Google Scholar
American Psychiatric Association (1968). Diagnostic and statistical manual for mental disorders (2nd ed.). Washington, DC: Author.Google Scholar
American Psychiatric Association (1980). Diagnostic and statistical manual for mental disorders (3rd ed.). Washington, DC: Author.Google Scholar
American Psychiatric Association (1987). Diagnostic and statistical manual for mental disorders (3rd ed., rev.). Washington, DC: Author.Google Scholar
American Psychiatric Association (1994). Diagnostic and statistical manual for mental disorders (4th ed.). Washington, DC: Author.Google Scholar
American Psychiatric Association (2000). Diagnostic and statistical manual for mental disorders (4th ed., Text Revision). Washington, DC: Author.Google Scholar
American Psychiatric Association (2013). Diagnostic and statistical manual for mental disorders (5th ed.). Washington, DC: Author.Google Scholar
Arnold, L.E., Abikoff, H.B., Cantwell, D.P., Conners, C.K., Elliott, G., Greenhill, L.L., & Wells, K.C. (1997). The National Institute of Mental Health collaborative multimodal treatment study of children with ADHD (the MTA): Design challenges and choices. Archives of General Psychiatry, 54, 865870.Google Scholar
Aylward, E.H., Reiss, A.L., Reader, M.J., Singer, H.S., Brown, J.E., & Denckla, M.B. (1996). Basal ganglia volumes in children with attention-deficit hyperactivity disorder. Journal of Child Neurology, 11, 112115.Google Scholar
Barkley, R.A. (1997). Behavioral inhibition, sustained attention, and executive functions: Constructing a unifying theory of ADHD. Psychological Bulletin, 121, 6594.Google Scholar
Barkley, R.A. (2002). International consensus statement on ADHD. Clinical Child and Family Psychology Review, 5(2), 89111.Google Scholar
Barkley, R.A., Murphy, K.R., & Fischer, M. (2008). Identifying new symptoms of ADHD in adulthood. In R.A Barkley, K.R. Murphy, & M. Fischer (Eds.), ADHD in adults (pp. 170204). New York: Guilford Press.Google Scholar
Bosco, B.P., & Bona, A. (2016). Changes in academic demands and ADHD in young children. JAMA Pediatrics . Published online February 22, 2016.Google Scholar
Bradley, C. (1937). The behavior of children receiving Benzedrine. The American Journal of Psychiatry, 3, 577585.Google Scholar
Bruchmuller, K., Margraf, J., & Schneider, S. (2012). Is ADHD diagnosed in accord with diagnostic criteria? Overdiagnosis and influence of client gender on diagnosis. Journal of Consulting and Clinical Psychology, 80, 128138.Google Scholar
Castellanos, F.X., & Aoki, Y. (2016). Intrinsic functional connectivity in attention-deficit/hyperactivity disorder: A science in development. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, 1, 253261. doi: 10.1016/j.bpsc.2016.03.004 Google ScholarPubMed
Clements, S.D. (1966). Minimal brain dysfunction in children: Terminology and identification: Phase one of a three-phase project. NINDS Monographs, 9 (Public Health Service Bulletin No.1415). Washington, DC: U.S. Department of Health, Education and Welfare.Google Scholar
Cole, W., Mostofsky, S.H., Gidley Larson, J.C., Denckla, M.B., & Mahone, E.M. (2008). Age related change in motor subtle signs among girls and boys with ADHD. Neurology, 71(19), 15141520. doi: 10.1212/01.wnl.0000334275.57734.5f CrossRefGoogle ScholarPubMed
Cortese, S., Kelly, C., Chabernaud, C., Proal, E., Di Martino, A., Milham, M.P., &Castellanos, F.X. (2012). Toward systems neuroscience of ADHD: A meta-analysis of 55 fMRI studies. American Journal of Psychiatry, 169(10), 10381055. doi: 10.1176/appi.ajp.2012.11101521 CrossRefGoogle ScholarPubMed
Couto, J.M., Gomex, L., Wigg, K., Ickowicz, K., Pathare, T., Malone, M., & Barr, C.L. (2009). Association of ADHD with a candidate region for reading disabilities on chromosome 6p. Biological Psychiatry, 66, 368375.CrossRefGoogle ScholarPubMed
Davies, W. (2014). Sex differences in attention deficit hyperactivity disorder: Candidate genetic and endocrine mechanisms. Frontiers in Neuroendocrinology, 35, 331346.Google Scholar
Denckla, M.B. (2005). Executive function. In D. Gozal, & D.L. Molfese (Eds.), Attention deficit hyperactivity disorder: From genes to patients (pp. 165184). Totowa, NJ: Humana Press.Google Scholar
Denckla, M.B., & Rudel, R.G. (1978). Anomalies of motor development in hyperactive boys. Annals of Neurology, 3, 231233.Google Scholar
Diamond, A. (2000). Close interrelation of motor development and cognitive development and of the cerebellum and prefrontal cortex. Child Development, 71, 4456.CrossRefGoogle ScholarPubMed
Dirlikov, B., Rosch, K.S., Crocetti, D., Denckla, M.B., Mahone, E.M., & Mostofsky, S.H. (2014). Distinct frontal lobe morphology in girls and boys with ADHD. Neuroimage: Clinical, 10, 222229. doi: 10.1016/j.nicl.2014.12.010 Google Scholar
Doshi, J.A., Hodgkins, P., Kahle, J., Sikirica, V., Cangelosi, M.J., Setyawan, J., & Neumann, P.J. (2012). Economic impact of childhood and adult attention-deficit/hyperactivity disorder in the United States. Journal of the American Academy of Child and Adolescent Psychiatry, 51, 9901000.CrossRefGoogle ScholarPubMed
Douglas, V.I., & Peters, K.G. (1979). Toward a clearer definition of the attentional deficits of hyperactive children. In G.A. Hale & M. Lewis (Eds.), Attention and the developments of cognitive skills (pp. 173248). New York: Plenum Press.CrossRefGoogle Scholar
Eme, R.F., (1992). Selective female affliction in the developmental disorders of childhood: A review. Journal of Clinical Child Psychology, 21, 354364.Google Scholar
Fair, D.A., Posner, J., Nagel, B.J., Bathula, D., Costa Dias, T.G., Mills, K.L., & Nigg, J.T. (2010). Atypical default network connectivity in youth with attention-deficit/hyperactivity disorder. Biological Psychiatry, 68, 10841091. doi: 10.1016/j.biopsych.2010.07.003 Google Scholar
Faraone, S.V., Asherson, P., Banaschewski, T., Biederman, J., Buitelaar, J.K., Ramos-Quiroga, J.A., & Franke, B. (2015). Attention-deficit/hyperactivity disorder. Nature Reviews: Disease Primers, 1, 15020. doi: 10.1038/nrdp.2015.20 Google Scholar
Fletcher, J.M. (2014). The effects of childhood ADHD on adult labor market outcomes. Health Economics, 23, 159181.Google Scholar
Ghemlin, D., Fuermaier, A.B.M., Walther, S., Debelak, R., Rentrop, M., Westermann, C., & Weisbrod, M. (2014). Intraindividual variability in inhibitory function in adults with ADHD – An ex-Gaussian approach. PLoS One. doi: 10.1371/journal.pone.0112298 Google Scholar
Gidley Larson, J.C., Mostofsky, S.H., Goldberg, M., Cutting, L., Denckla, M.B., & Mahone, E.M. (2007). Effects of gender and age on motor exam in typically developing children. Developmental Neuropsychology, 32(1), 543562. doi: 10.1080/87565640701361013 Google Scholar
Gilbert, D.L., Isaacs, K.M., Augusta, M., MacNeil, L.K., & Mostofsky, S.H. (2011). Motor cortex inhibition: A marker of ADHD behavior and motor development in children. Neurology, 76, 615621.Google Scholar
Gray, J.A. (1982). The neuropsychology of anxiety. New York: Oxford University Press.Google Scholar
Greenhill, L., Kollins, S., Abikoff, H., McCracken, J., Riddle, M., Swanson, J., & Cooper, T. (2006). Efficacy and safety of immediate-release methylphenidate treatment for preschoolers with ADHD. Journal of the American Academy of Child and Adolescent Psychiatry, 45, 12841293. doi: 10.1097/01.chi.0000235077.32661.61 Google Scholar
Heilman, K.M., Voeller, K.K.S., & Nadeau, S.E. (1991). A possible pathophysiologic substrate of attention deficit hyperactivity disorder. Journal of Child Neurology, 6(Suppl.), S76S81.Google Scholar
Hinshaw, S.P., & Arnold, L.E., & the MTA Cooperative Group (2015). Attention-deficit hyperactivity disorder, multimodal treatment, and longitudinal outcome: Evidence, paradox, and challenge. WIREs Cognitive Science, 6, 3952. doi: 10.1002/wcs.1324 CrossRefGoogle ScholarPubMed
Hinshaw, S.P., & Ellison, K. (2016). ADHD: What everyone needs to know. New York: Oxford University Press.Google Scholar
Hinshaw, S.P., Owens, E.B., Zalecki, C., Huggins, S.P., Montenegro-Nevado, A.J., Schrodek, E., &Swanson, E.N. (2012). Prospective follow-up of girls with attention-deficit/hyperactivity disorder into early adulthood: Continuing impairment includes elevated risk for suicide attempts and self-injury. Journal of Consulting and Clinical Psychology, 80, 10411051.CrossRefGoogle ScholarPubMed
Hinshaw, S.P., & Scheffler, R.M. (2014, Feb. 23). Expand pre-K, not ADHD. NY Times, Op-Ed.Google Scholar
Hinshaw, S.P., Scheffler, R.M., Fulton, B.D., Aase, H., Banaschewski, T., Cheng, W., & Weiss, M.D. (2011). International variation in treatment procedures for ADHD: Social context and recent trends. Psychiatric Services, 62, 459464.Google Scholar
Hooper, S.R., & Williams, E.A. (2005). Attention deficit hyperactivity disorder and learning disabilities. In D. Gozal & D.L. Molfese (Eds.), Attention deficit hyperactivity disorder: From genes to patients (pp. 215254). Totowa, NJ: Humana Press.Google Scholar
Insel, T., Cuthbert, B., Garvey, M., Heinssen, R., Pine, D., Quinn, K., & Wang, P. (2010). Research Domain Criteria (RDoC): Toward a new classification framework for research on mental disorders. American Journal of Psychiatry, 167, 348351.Google Scholar
Jacobson, L.A., Murphy-Bowman, S.C., Pritchard, A.E., Tart-Zelvin, A., Zabel, T.A., & Mahone, E.M. (2012). Factor structure of a sluggish cognitive tempo scale in clinically referred children. Journal of Abnormal Child Psychology, 40(8), 13271337. doi: 10.1007/s10802-012-9643-6 Google Scholar
Kooij, S.J.J., Bejerot, S., Blackwell, A., Caci, H., Casas-Brugué, M., Carpentier, P.J., & Asherson, P. (2010). European consensus statement on diagnosis and treatment of adult ADHD: The European Network Adult ADHD. BMC Psychiatry, 10(67), 124. http://www.biomedcentral.com/1471-244X/10/67.Google Scholar
Kuntsi, J., & Klein, C. (2012). Intraindividual variability in ADHD and its implications for research of causal links. Current Topics in Behavioral Neuroscience, 9, 6791. doi: 10.1007/7854_2011_145 CrossRefGoogle ScholarPubMed
Larson, K., Russ, S.A., Kahn, R.S., & Halfon, N. (2011). Patterns of comorbidity, functioning, and service use for US children with ADHD. Pediatrics, 127, 462467.Google Scholar
Lee, R.W.Y., Jacobson, L.A., Pritchard, A.E., Ryan, M., Yu, Q., Denckla, M.B., & Mahone, E.M. (2015). Jitter reduces response time variability in ADHD: An ex-Gaussian analysis. Journal of Attention Disorders, 19, 794804. doi: 10.1177/1087054712464269 Google Scholar
Lenroot, R.K., Gogtay, N., Greenstein, D.K., Wells, E.M., Wallace, G.L., Clasen, L.S. et al. (2007). Sexual dimorphism of brain developmental trajectories during childhood and adolescence. Neuroimage, 36, 10651073.CrossRefGoogle ScholarPubMed
Luman, M., Van Meel, C.S., Oosterlaan, J., Sergeant, J.A., & Guerts, H.M. (2009). Does reward frequency or magnitude drive reinforcement-learning in attention-deficit/hyperactivity disorder? Psychiatry Research, 168, 222229.Google Scholar
Mahone, E.M., Crocetti, D., Ranta, M.E., Gaddis, A., Cataldo, M., Slifer, K.J., & Mostofsky, S.H. (2011). A preliminary neuroimaging study of preschool children with ADHD. The Clinical Neuropsychologist, 25, 10091028.Google Scholar
Mahone, E.M., Hagelthorn, K.M., Cutting, L.E., Schuerholz, L.J., Pelletier, S.F., Rawlins, C., & Denckla, M.B. (2002). Effects of IQ on executive function measures in children with ADHD. Child Neuropsychology, 8, 5265. doi: 10.1076/chin.8.1.52.8719 Google Scholar
Mahone, E.M., Ranta, M.E., Crocetti, D., O’Brien, J.W., Kaufmann, W.E., Denckla, M.B., & Mostofsky, S.H. (2011). Comprehensive examination of frontal regions in boys and girls with attention-deficit/hyperactivity disorder. Journal of the International Neuropsychological Society, 17, 10471057.Google Scholar
Miller, M., Loya, F., & Hinshaw, S.P. (2013). Executive functions in girls with and without childhood ADHD: Developmental trajectories and associations with symptom change. Journal of Child Psychology and Psychiatry, 54, 10051015.Google Scholar
MTA Cooperative Group (1999a). A 14-month randomized clinical trial of treatment strategies for attention-deficit hyperactivity disorder. Archives of General Psychiatry, 56, 10731087.Google Scholar
MTA Cooperative Group (1999b). Moderators and mediators of treatment response for children with attention-deficit hyperactivity disorder. Archives of General Psychiatry, 56, 10881096.Google Scholar
MTA Cooperative Group (2004). National Institute of Mental Health multimodal treatment study of ADHD follow-up: 24-month outcomes of treatment strategies for attention-deficit hyperactivity disorder. Pediatrics, 113, 754761.CrossRefGoogle Scholar
National Health and Medical Research Council (2012). Clinical practice points on the diagnosis, assessment, and management of attention deficit hyperactivity disorder in children and adolescents. Australia: Australian Government National Health and Medical Research Council.Google Scholar
National Institute for Health and Clinical Excellence (NICE) (2009). Attention deficit hyperactivity disorder: Diagnosis and management of ADHD in children, young people and adults. London: British Psychological Society and Royal College of Psychiatrists.Google Scholar
Nichols, P., & Chen, T. (1981). Minimal brain dysfunction: A prospective study. Hillside, NJ: Erlbaum Associates.Google Scholar
Nigg, J.T., & Casey, B.J. (2005). An integrative theory of attention–deficit hyperactivity disorder based on the cognitive and affective neurosciences. Development and Psychopathology, 17, 785806. doi: 10.10170S0954579405050376 Google Scholar
Nigg, J.T., Willcutt, E.G., Doyle, A.E., & Sonuga-Barke, E.J.S. (2005). Causal heterogeneity in attention-deficit/hyperactivity disorder: Do we need neuropsychologically impaired subtypes? Biological Psychiatry, 57, 12241230.Google Scholar
NIH Consensus Statement (1998). Diagnosis and treatment of attention deficit hyperactivity disorder, 16(2), 137.Google Scholar
O’Brien, J.W., Dowell, L.R., Mostofsky, S.H., Denckla, M.B., & Mahone, E.M. (2010). Neuropsychological profile of executive function in girls with attention-deficit/hyperactivity disorder. Archives of Clinical Neuropsychology, 25(7), 656670. doi: 10.1093/arclin/acq050 Google Scholar
Pastor, P., Reuben, C., Duran, C., & Hawkins, L. (2015). Association between diagnosed ADHD and selected characteristics among children aged 4-17 years: United States, 2011-2013. NCHS Data Brief, 201, 18.Google Scholar
Pliszka, S., & the AACAP Workgroup on Quality Issues (2007). Practice parameter for the assessment and treatment of children and adolescents with attention-deficit/hyperactivity disorder. Journal of the American Academy of Child and Adolescent Psychiatry, 46, 894921.Google Scholar
Polanczyk, G., de Lima, M.S., Horta, B.L., Biederman, J., & Rohde, L.A. (2007). The worldwide prevalence of ADHD: A systematic review and meta-regression analysis. American Journal of Psychiatry, 164, 942948.Google Scholar
Qiu, A., Crocetti, D., Adler, M., Mahone, E.M., Denckla, M.B., Miller, M.I., & Mostofsky, S.H. (2009). Basal ganglia volume and shape in children with attention deficit hyperactivity disorder. American Journal of Psychiatry, 166, 7482. doi: 10.1176/appi.ajp.2008.08030426 Google Scholar
Quay, H.C. (1988). The behavioral reward and inhibition systems in childhood behavioral disorder. In L.M. Bloomingdale (Ed.), Attention deficit disorder III: New research in treatment, psychopharmacology, and attention (pp. 176186). New York: Pergamon.Google Scholar
Riddle, M.A., Yershova, K., Lazzaretto, D., Paykina, N., Yenokyan, G., Greenhill, L., & Posner, K. (2013). The preschool attention-deficit hyperactivity disorder treatment study (PATS) 6-year follow-up. Journal of the American Academy of Child and Adolescent Psychiatry, 52, 264278.Google Scholar
Ryan, M., Martin, R.B., Denckla, M.B., Mostofsky, S.H., & Mahone, E.M. (2010). Inter-stimulus jitter facilitates response control in children with ADHD. Journal of the International Neuropsychological Society, 16, 388393. doi: 10.1017/S1355617709991305 Google Scholar
Sergeant, J.A. (2000). The cognitive-energetic model: An empirical approach to attention-deficit hyperactivity disorder. Neuroscience and Biobehavioral Reviews, 24, 712.Google Scholar
Sergeant, J., Guerts, H., Huijbregts, S., Sheres, A., & Oosterlaan, J. (2003). The top and bottom of ADHD: A neuropsychological perspective. Neuroscience and Biobehavioral Reviews, 27, 583592.Google Scholar
Sergeant, J.A., Willcutt, E., & Nigg, J. (2007). How clinically functional are executive function measures of ADHD? In D. Shaffer, E. Leibenluft, L.A. Rohde, P. Sirovatka, & D.A. Regier (Eds.), Externalizing disorders of childhood: Refining the research agenda for DSM-V. Arlington, VA: American Psychiatric Association.Google Scholar
Shaw, P., Eckstrand, K., Sharp, W., Blumenthal, J., Lerch, J.P., Greenstein, D., & Rapoport, J.L. (2007). Attention-deficit/hyperactivity disorder is characterized by a delay in cortical maturation. Proceedings of the National Academy of Sciences of the United States of America, 104, 1964919654.Google Scholar
Shaw, P., Gilliam, M., Liverpool, M., Weddle, C., Malek, M., Sharp, W., & Giedd, J. (2011). Cortical development in typically developing children with symptoms of hyperactivity and impulsivity: Support for a dimensional view of attention deficit hyperactivity disorder. The American Journal of Psychiatry, 168, 143151.Google Scholar
Shaw, P., & Polanczyk, G.V. (2017). Combining epidemiological and neurobiological perspectives to characterize the lifetime trajectories of ADHD. European Journal of Child and Adolescent Psychiatry, 26, 139141. doi: 10.1007/s00787-017-0944-8 Google Scholar
Sobel, L.J., Bansal, R., Maia, T.V., Sanchez, J., Mazzone, L., Durkin, K., & Peterson, B.S. (2010). Basal ganglia surface morphology and the effects of stimulant medications in youth with attention deficit hyperactivity disorder. American Journal of Psychiatry, 67, 977986. doi: 10.1176/appi.ajp.2010.09091259 Google Scholar
Sonuga-Barke, E. (2003). The dual pathway model of AD/HD: An elaboration of neuro-developmental characteristics. Neuroscience and Biobehavioral Reviews, 27, 593604.Google Scholar
Sonuga-Barke, E.J. (2010). Disambiguating inhibitory dysfunction in attention-deficit/hyperactivity disorder: toward the decomposition of developmental brain phenotypes. Biological Psychiatry, 67, 599601. doi: 10.1016/j.biopsych.2010.01.017 Google Scholar
Sonuga-Barke, E.J., Brandeis, D., Cortese, S., Daley, D., Ferrin, M., Holtmann, M., … the European ADHD Guidelines Group. (2013). Nonpharmacological interventions for ADHD: Systematic review and meta-analyses of randomized controlled trials of dietary and psychological treatments. American Journal of Psychiatry, 170, 275289.Google Scholar
Sonuga-Barke, E.J., Sergeant, J.A., Nigg, J., & Willcutt, E., (2008). Executive dysfunction and delay aversion in attention deficit hyperactivity disorder: Nosologic and diagnostic implications. Child and Adolescent Psychiatric Clinics of North America, 17, 367384. doi: 10.1016/j.chc.2007.11.008 Google Scholar
Sonuga-Barke, E., Paraskevi, B., & Thompson, M. (2010). Beyond the dual pathway model: Evidence for the dissociation of timing, inhibitory, and delay-related impairments in attention-deficit hyperactivity disorder. Journal of the American Academy of Child and Adolescent Psychiatry, 49, 345355.Google ScholarPubMed
Sun, H., Yuan, F., Shen, X., Xiong, G., & Wu, J. (2014). Role of COMT in ADHD: A systematic meta-analysis. Molecular Neurobiology, 49, 251261.Google Scholar
Tamm, L., Barnea-Goraly, N., & Reiss, A.L. (2012). Diffusion tensor imaging reveals white matter abnormalities in attention-deficit/hyperactivity disorder. Psychiatry Research: Neuroimaging, 202(3), 150154. doi: 10.1016/j.pscychresns.2012.04.001 Google Scholar
Taylor, E., Dopfner, M., Sergeant, J., Asherson, P., Banaschewski, T., Buitelaar, J., & Zuddas, A. (2004). European clinical guidelines for hyperkinetic disorder-first upgrade. European Journal of Child and Adolescent Psychiatry, 13(Suppl. 1), 1/71/30. doi: 10.1007/s00787-004-1002-x Google Scholar
Todd, R.D., Huang, H., & Henderson, C.A. (2008). Poor utility of the age of onset criterion for DSM-IV attention deficit/hyperactivity disorder: Recommendations for DSM-V and ICD-11. The Journal of Child Psychology and Psychiatry, 49, 942949. doi: 10.1111/j.1469-7610.2008.01892.x Google Scholar
Tung, I., Li, J.J., Meza, J.I., Jezior, K.L., Kianmahd, J.S.V., Hentschel, P.G., O’Neil, P.M., & Lee, S.S. (2016). Patterns of comorbidity among girls with ADHD: A meta-analysis. Pediatrics, 138(4), e20160430.Google Scholar
Valo, S., & Tannock, R. (2010). Diagnostic instability of DSM-IV ADHD subtypes: Effects of informant source, instrumentation, and methods for combining symptom reports. Journal of Clinical Child and Adolescent Psychology, 39, 749760. doi: 10.1080/15374416.2010.517172 CrossRefGoogle ScholarPubMed
Van Lieshout, M., Luman, M., Twisk, J.W., van Ewijk, H., Groenman, A.P., Thissen, A.J., & Oosterlaan, J. (2016). A 6-year follow-up of a large European cohort of children with attention-deficit/hyperactivity disorder combined subtype: Outcomes in late adolescence and young adulthood. European Journal of Child and Adolescent Psychiatry, 25, 10071017.Google Scholar
Willcutt, E.G., Nigg, J.T., Pennington, B.F., Solanto, M.V., Rohde, L.A., Tannock, R., & Lahey, B.B. (2012). Validity of the DSM-IV Attention Deficit/Hyperactivity Disorder symptom dimensions and subtypes. Journal of Abnormal Psychology, 121, 9911010. doi: 10.1037/a0027347991 CrossRefGoogle ScholarPubMed
World Health Organization (1978). The ICD-9 Classification Diseases, 9th Edition. Geneva, Switzerland: WHO.Google Scholar
World Health Organization (1993). The ICD-10 Classification of Mental and Behavioral Disorders: Diagnostic Criteria for Research. Geneva, Switzerland: WHO.Google Scholar
World Health Organization (2017). International Classification of Diseases, 10th Edition, Clinical Modifications (ICD-10-CM). Geneva, Switzerland: WHO.Google Scholar
Wu, Z., Yang, L., & Wang, Y. (2014). Applying imaging genetics to ADHD: The promises and the challenges. Molecular Neurobiology, 15, 449462.Google Scholar
Wyciszkiewicz, A., Pawlak, M.A., & Krawiec, K. (2017). Cerebellar volume in attention-deficit hyperactivity disorder (ADHD): Replication study. Journal of Child Neurology, 32, 215221. doi: 10.1177/0883073816678550 Google Scholar