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The role of dietary selenium in bovine mammary gland health and immune function

Published online by Cambridge University Press:  06 February 2009

S. Salman ,
A. Khol-Parisini ,
H. Schafft ,
M. Lahrssen-Wiederholt ,
H. W. Hulan ,
D. Dinse  and
J. Zentek
S. Salman*
Affiliation:
Institut für Tierernährung, Freie Universität Berlin, Brümmerstr 34, 14195Berlin, Germany
A. Khol-Parisini
Affiliation:
Institut für Tierernährung, Freie Universität Berlin, Brümmerstr 34, 14195Berlin, Germany
H. Schafft
Affiliation:
Bundesinstitut für Risikobewertung (BfR), Diedersdorfer Weg 1, 12277Berlin, Germany
M. Lahrssen-Wiederholt
Affiliation:
Bundesinstitut für Risikobewertung (BfR), Diedersdorfer Weg 1, 12277Berlin, Germany
H. W. Hulan
Affiliation:
Department of Biochemistry, Memorial University, St. John's, Newfoundland, A1B 3X9, Canada
D. Dinse
Affiliation:
Institut für Tierernährung, Freie Universität Berlin, Brümmerstr 34, 14195Berlin, Germany
J. Zentek
Affiliation:
Institut für Tierernährung, Freie Universität Berlin, Brümmerstr 34, 14195Berlin, Germany
*
*Corresponding author. E-mail: salmaan@zedat.fu-berlin.de
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Abstract

Mastitis is not only a major cause of economic losses to the dairy industry but also a major problem in ensuring the quality and safety of the milk, associated with high somatic cell counts and residues of antibiotics used for treatment. One innovative approach to protection against mastitis is to stimulate the animal's natural defense mechanisms. Technological advances in immunological research have increased our ability to exploit the immunity of the bovine mammary gland during periods of high susceptibility to disease. The trace element selenium affects the innate and the adaptive immune responses of the mammary gland through cellular and humoral activities. Substantial research has been carried out on the effect of selenium (Se) on the immune function of the mammary gland and subsequent improvement in bovine udder health and mastitis control. Levels higher than current recommendations and Se-yeast can potentially be used to enhance our capacity to modulate the physiological mechanisms of the bovine mammary gland to respond to infection. This article provides an overview of the most recent research in this field.

Keywords

seleniumimmune functiondairy cattlemilk quality and safetymastitisbovine mammary gland
Type
Review Article
Information
Animal Health Research Reviews , Volume 10 , Issue 1 , June 2009 , pp. 21 - 34
Copyright
Copyright © Cambridge University Press 2009

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