Hostname: page-component-8448b6f56d-tj2md Total loading time: 0 Render date: 2024-04-25T00:18:05.192Z Has data issue: false hasContentIssue false
  • English
  • Français

The time of detection of recessive visible genes with non-random mating

Published online by Cambridge University Press:  14 April 2009

Armando Caballero ,
Alison M. Etheridge  and
William G. Hill
Armando Caballero*
Affiliation:
Institute of Cell, Animal and Population Biology, University of Edinburgh, West Mains Road, Edinburgh EH9 3JT, Scotland
Alison M. Etheridge
Affiliation:
Department of Mathematics and Statistics, University of Edinburgh, Mayfield Road, Edinburgh EH9 3JZ, Scotland
William G. Hill
Affiliation:
Institute of Cell, Animal and Population Biology, University of Edinburgh, West Mains Road, Edinburgh EH9 3JT, Scotland
*
*Corresponding author
Rights & Permissions [Opens in a new window]

Summary

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

Expressions for the probability and average time of detection of a recessive visible gene in populations where there is partial selfing or partial full-sib mating are presented. A small increase in the proportion of inbred matings greatly reduces the average time until detection and increases the proportion detected. Unless the proportion of inbred matings or the population size is very small, the time and proportion detected are approximately independent of the population size.

Type
Research Article
Information
Genetics Research , Volume 60 , Issue 3 , December 1992 , pp. 201 - 207
Copyright
Copyright © Cambridge University Press 1992

References

Caballero, A., Keightley, P. D. & Hill, W. G. (1991). Strategies for increasing fixation probabilities of recessive mutations. Genetical Research 58, 129–138.CrossRefGoogle Scholar
Caballero, A. & Hill, W. G. (1992). Effective size of nonrandom mating populations. Genetics 130, 909–916.CrossRefGoogle ScholarPubMed
Feller, W. (1968). An Introduction to Probability Theory and its Applications, vol. 1, 3rd edn.New York: Wiley.Google Scholar
Hedrick, P. W. & Cockerham, C. C. (1986). Partial inbreeding: equilibrium heterozygosity and the heterozygosity paradox. Evolution 40, 856–861.CrossRefGoogle ScholarPubMed
Karlin, S. & Tavaré, S. (1981 a). The detection of a recessive 206 visible gene in finite populations. Genetical Research 37, 33–46.CrossRefGoogle Scholar
Karlin, S. & Tavaré, S. (1981 b). The detection of particular genotypes in finite populations. I. Natural selection effects. Theoretical Population Biology 19, 187–214.CrossRefGoogle ScholarPubMed
Karlin, S. & Tavare, S. (1981 c). The detection of particular genotypes in finite populations. II. The effects of partial penetrance and family structure. Theoretical Population Biology 19, 215–229.CrossRefGoogle ScholarPubMed
Kemeny, J. G. & Snell, J. L. (1960). Finite Markov chains. New York: Van Nostrand.Google Scholar
Li, C. C. (1976). First Course in Population Genetics. Boxwood: Pacific Grove, California.Google Scholar
Robertson, A. (1978). The time of detection of recessive visible genes in small populations. Genetical Research 31, 255–264.CrossRefGoogle Scholar
Santiago, E. (1989). Time of detection of recessive genes: effects of system of mating and number of examined individuals. Theoretical and Applied Genetics 77, 867–872.CrossRefGoogle ScholarPubMed
Schemske, D. W. & Lande, R. (1985). The evolution of selffertilization and inbreeding depression in plants. II. empirical observations. Evolution 39, 41–52.Google ScholarPubMed