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Antimicrobial activity studies of the binuclear metal complexes derived from tridentate Schiff base ligands

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Abstract

Three novel tridentate Schiff base ligands derived from␣the 3-hydroxysalicylaldehyde (H2L1), 4-hydroxysalicylaldehyde (H2L2) and 5-bromosalicylaldehyde (H2L3) with a new amine N-(pyridyl)-2-hydroxy-3-methoxy-5-aminobenzylamine (2) have been prepared. The ligands and their metal complexes have been characterized by elemental analyses, conductivity and magnetic susceptibility measurements, i.r., electronic absorption and 1H and 13C n.m.r. spectroscopy. All complexes are binuclear and, in some, the H2O molecules are coordinated to the metal ion. Antimicrobial activities of the ligands and their complexes have been tested against to the Bacillus subtilis IMG 22 (bacteria), Micrococcus luteus LA 2971 (bacteria) Saccharamyces cerevisiae WET 136 (yeast), and Candida albicans CCM 314 (yeast). Thermal properties of all complexes have been studied by t.g. and d.t.a techniques.

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Tümer, M., Köksal, H., Sener, M.K. et al. Antimicrobial activity studies of the binuclear metal complexes derived from tridentate Schiff base ligands. Transition Metal Chemistry 24, 414–420 (1999). https://doi.org/10.1023/A:1006973823926

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