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Osteoinduction by calcium phosphate biomaterials

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Abstract

Different materials were implanted in muscles of dogs to study the osteoinduction of calcium phosphate biomaterials. Bone formation was only seen in calcium phosphate biomaterials with micropores, and could be found in hydroxyapatite (HA) ceramic, tricalcium phosphate/hydroxyapatite ceramic (BCP), β-TCP ceramic and calcium phosphate cement. The osteoinductive potential was different in different materials. The results indicate that osteoinduction can be a property of calcium phosphate biomaterials when they exhibit specific chemical and structural characteristics. © 1998 Kluwer Academic Publishers

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Authors and Affiliations

  1. Institute of Materials Sciences and Technology, Sichuan Union University, Chengdu, 610064, People's Republic of China

    Huipin Yuan, Zongjian Yang, Yubao Li & Xingdong Zhang

  2. Biomaterials Research Group, Leiden University, and IsoTis BV, Professor Bronkhorstlaan 10, 3723 MB, Bilthoven, The Netherlands

    J. D. De Bruijn & K. De Groot

Authors
  1. Huipin Yuan
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  2. Zongjian Yang
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  3. Yubao Li
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  4. Xingdong Zhang
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  5. J. D. De Bruijn
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  6. K. De Groot
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Yuan, H., Yang, Z., Li, Y. et al. Osteoinduction by calcium phosphate biomaterials. Journal of Materials Science: Materials in Medicine 9, 723–726 (1998). https://doi.org/10.1023/A:1008950902047

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