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Synthesis of 3-(5-Aryl-1,3,4-oxadiazol-2-yl)chromones

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Abstract

A general procedure was proposed for the synthesis of 3-(5-aryl-1,3,4-oxadiazol-2-yl)chromones by reaction of 3-formylchromone with aroylhydrazines, transformation of the corresponding acylhydrazones into 1,3-dipoles by the action of bromine in the presence of sodium acetate, and intramolecular ring closure.

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Authors and Affiliations

  1. Sinxiang University, China

    L. Tsao, V. Van, G. Sun & Yu. Lyu

  2. Tientsin Medical University, Tientsin, China

    L. Tsao, V. Van, G. Sun & Yu. Lyu

  3. State Central Laboratory, Nankai University, China

    L. Tsao, V. Van, G. Sun & Yu. Lyu

Authors
  1. L. Tsao
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  2. V. Van
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  3. G. Sun
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  4. Yu. Lyu
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Tsao, L., Van, V., Sun, G. et al. Synthesis of 3-(5-Aryl-1,3,4-oxadiazol-2-yl)chromones. Russian Journal of General Chemistry 71, 767–769 (2001). https://doi.org/10.1023/A:1012369621168

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  • DOI: https://doi.org/10.1023/A:1012369621168

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