Abstract
A microanalytical system based on a microfluidics/electrochemical detection scheme was developed. The microfluidic platform was fabricated based on a multi-layer lamination method. Fluidic microchannels were produced by sandwiching laser-machined adhesive-backed polyimide gaskets between layers of the device. Individual components, such as microfabricated piezoelectrically actuated pumps and a microelectrochemical cell were designed and fabricated into plug-in modules which can be readily plugged into (or unplugged from) the microfluidic platform. This allowed rapid change-out and repair of individual components by incorporating “plug and play” concepts now standard in PC's. The detection of lead and chlorophenols were performed with the microanalytical system to demonstrate the capabilities of this new technology for on-site environmental characterization and for real-time non-invasive biomonitoring of toxic chemical mixtures.
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Lin, Y., Timchalk, C.A., Matson, D.W. et al. Integrated Microfluidics/Electrochemical Sensor System for Monitoring of Environmental Exposures to Lead and Chlorophenols. Biomedical Microdevices 3, 331–338 (2001). https://doi.org/10.1023/A:1012417000516
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DOI: https://doi.org/10.1023/A:1012417000516