Abstract
A route for the fabrication of porous hydroxyapatite ceramics having two populations of open pores is reported. The bodies are prepared by sintering the spherical gelatin/hydroxyapatite granules. As the result, ceramics containing intragranular small-size pores and intergranular large-size interconnecting pores are obtained. The pore size and content are dependent on the route. Ceramics can generally be applied as bone replacement materials where the interconnections in the intergranular pores are the pathway to conduct cells and vessels for the bone ingrowth, whereas the intragranular pores can be filled with a drug, e.g. to eliminate infections.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
H. Aoki, “Science and Medical Application of Hydroxyapatite” (JAAS, Tokyo, 1991) p. 137.
L. L. Hench, in “Ceramics and Society”, edited by P. Vincenzini (Techna, Faenza, 1995) p. 101.
K. A. Hing, S. M. Best and W. Bonfield, J. Mater. Sci.: Mater. Med. 10 (1999) 135.
Y. L. Liu, J. Schoenaers, K. De Groot, J. R. De Wijn and E. Schepers, ibid. 11 (2000) 711.
A. Uchida, S. M. N. Nade, E. R. Mccartney and W. Ching, J. Bone Joint Surg. 66B (1984) 269.
K. A. Hing, S. M. Best, K. E. Tanner, W. Bonfield and P. A. Revell, J. Mater. Sci.: Mater. Med. 10 (1999) 663.
P. S. Eggli, W. Mueller and R. K. Schenk, Clin. Orthop. Rel. Res. 232 (1988) 127.
A. Krajewski, A. Ravaglioli, E. Roncari, P. Pinsco and L. Montanari, J. Mater. Sci.: Mater. Med. 11 (2000) 763.
W. Paul and C. T. Sharma, ibid. 10 (1999) 383.
W. Paul and C. T. Sharma, J. Mater. Sci. Lett. 14 (1995) 224.
M. Itokazu, M. Esaki, K. Yamamoto, T. Tanemori and T. Kasai, J. Mater. Sci.: Mater. Med. 10 (1999) 249.
J. X. Lu, B. Flautre, K. Anselme, P. Hardouin, A. Gallur, M. Descamps and B. Thierry, ibid. 10 (1999) 111.
R. E. Holmes, V. Mooney, R. Bucholz and A. Tencher, Clin. Orthop. Rel. Res. 188 (1984) 252.
M. Yamamoto, Y. Tabata, H. Kawasaki and Y. Ikada, J. Mater. Sci.: Mater. Med. 11 (2000) 213.
J. J. Klawitter and S. F. Hulbert, J. Biomed. Mater. Res. Symp. 2 (1971) 161.
R. A. Smith, M. W. Mosesson, A. U. Daniels and T. K. Gartner, J. Mater. Sci.: Mater. Med. 11 (2000) 279.
V. P. Orlovski, Z. A. Ezhova, G. V. Rodicheva, E. M. Koval, G. E. Sukhanova and L. A. Tezikova, J. Inorg. Chem. 37 (1992) 881.
S. M. Barinov and V. Ja. Shevchenko, “Strength of Engineering Ceramics” (Science, Moscow, 1996) p. 19.
K. K. Strelov, “Structure and Properties of Refractories” (Metallurgy, Moscow, 1972) p. 216.
G. N. Dulnev and Yu. P. Zarichnjak, “Heat Conductivity of Mixtures and Composite Materials” (Energy, Leningrad, 1974) p. 264.
M. G. Kaganer, “Heat Insulation in Low Temperatures Technology” (Mashinostrojenije, Moscow, 1966) p. 275.
Yu. L. Krasulin, V. N. Timofeev, S. M. Barinov, A. B. Ivanov, A. N. Asonov and G. D. Shnyrev, “Porous Structural Ceramics” (Metallurgy, Moscow, 1980) p. 73.
R. A. Andrievski, Powder Metal. N1 (1982) 37.
R. A. Andrievski and I. I. Spivak, “Strength of Refractory Compounds and Related Materials” (Metallurgy, Tcheljabinsk, 1989) p. 239.
W. Suchanek and M. Yoshimura, J. Mater. Res. 13 (1998) 94.
K. Ioku, K. Yanagisawa, N. Yamasaki, H. Kurosawa, K. Shibura and H. Yokozeki, Bio-Med. Mater. and Eng. 3 (1993) 137.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Komlev, V.S., Barinov, S.M. Porous hydroxyapatite ceramics of bi-modal pore size distribution. Journal of Materials Science: Materials in Medicine 13, 295–299 (2002). https://doi.org/10.1023/A:1014015002331
Issue Date:
DOI: https://doi.org/10.1023/A:1014015002331