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Manganese-Catalyzed Carbomagnesation of Alkynes

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Abstract

The development of manganese-catalyzed carbomagnesation of alkynes is reviewed. Manganese salts mediate the efficient addition of a variety of Grignard reagents to alkynes. Allyl, aryl, and alkyl Grignard reagents participate in these reactions. In many cases, a hetero atom such as oxygen or nitrogen in substrates facilitates the addition reaction. Stoichiometric carbometalation reactions with manganese ate complexes are also discussed, as is cyclization of 1,6-diynes and 1,6-enynes via carbometalation with triallylmanganate.

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Authors and Affiliations

  1. Department of Material Chemistry, Graduate School of Engineering, Kyoto University, Sakyo-ku, Kyoto, 606-8501, Japan

    Hiroshi Shinokubo & Koichiro Oshima

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  1. Hiroshi Shinokubo
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  2. Koichiro Oshima
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Shinokubo, H., Oshima, K. Manganese-Catalyzed Carbomagnesation of Alkynes. Catalysis Surveys from Asia 7, 39–46 (2003). https://doi.org/10.1023/A:1023432624548

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