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Cytogenetic Effects of Antibodies to γ-Interferon in Ultralow Doses

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Abstract

Single and course administration of ultralow doses of antibodies γ-interferon did not increase the incidence of cytogenetic abnormalities in bone marrow cells from BALB/c mice and produced no genotoxic effect on Drosophila melanogaster wing cells in the test of somatic mosaicism.

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REFERENCES

  1. A. D. Durnev, Yu. A. Revazova, O. L. Verstakova, et al., Manual on Experimental (Preclinical) Studies of New Pharmacological Preparations [in Russian], Moscow (2000), pp. 47-60.

  2. L. P. Zakharenko and I. K. Zakharov, Genetika, 32,No. 6, 755-758 (1996).

    Google Scholar 

  3. V. N. Orlov, G. A. Chudinovskaya, and E. P. Kryukova, Chromosome Sets in Mammals [in Russian], Moscow (1976).

  4. H. Frei and F. E. Wurgler, Mutat. Res., 203, 297-308 (1988).

    Google Scholar 

  5. B. Kaplan, Prof. Care Mother Child, 4,No. 5 (1994).

  6. B. Poitevin, Bull. WHO, 77,No. 2, 160-166 (1999).

    Google Scholar 

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Authors and Affiliations

  1. Tomsk Research Center, Siberian Division of the Russian Academy of Medical Sciences, Institute of Pharmacology, Russia

    O. L. Voronova, O. P. Rogozina, A. V. Martyushev, S. A. Sergeeva, O. I. Epstein, A.M. Dygai & E.D. Goldberg

  2. “Materia Medica Holding” Research-and-Production Company, Moscow

    O. L. Voronova, O. P. Rogozina, A. V. Martyushev, S. A. Sergeeva, O. I. Epstein, A.M. Dygai & E.D. Goldberg

Authors
  1. O. L. Voronova
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  2. O. P. Rogozina
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  3. A. V. Martyushev
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  4. S. A. Sergeeva
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  5. O. I. Epstein
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  6. A.M. Dygai
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  7. E.D. Goldberg
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Voronova, O.L., Rogozina, O.P., Martyushev, A.V. et al. Cytogenetic Effects of Antibodies to γ-Interferon in Ultralow Doses. Bulletin of Experimental Biology and Medicine 135 (Suppl 7), 65–66 (2003). https://doi.org/10.1023/A:1024730829988

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  • DOI: https://doi.org/10.1023/A:1024730829988

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