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Poly(vinyl alcohol) as versatile biomaterial for potential biomedical applications

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Abstract

In this paper, we present some new case examples where the chemical versatility of poly (vinyl alcohol) (PVA) can be used for potential biomedical applications. PVA, the polymeric material used for designing new nanostructured devices, is water soluble, biocompatible and has excellent physical properties. We point out the possibility of obtaining wall-to-wall chemical hydrogels as well as microgels without diminishing the biocompatibility available in the starting PVA material. Injectability is another important factor to take into account in controlled drug delivery for gene therapy. In this respect, in this paper, established and more innovative methods are prospected in order to obtain particles with dimensions suitable for these applications.

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Authors and Affiliations

  1. Department of Chemical Sciences and Technologies and INFM section B, University of Rome “Tor, Vergata”, Italy

    Gaio Paradossi, Francesca Cavalieri & Ester Chiessi

  2. Department of Chemical Engineering, Chemistry and Material Science, Polytechnic University of Brooklyn, New York, USA

    Chiara Spagnoli & Mary K. Cowman

Authors
  1. Gaio Paradossi
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  2. Francesca Cavalieri
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  3. Ester Chiessi
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  4. Chiara Spagnoli
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  5. Mary K. Cowman
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Correspondence to Gaio Paradossi.

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Paradossi, G., Cavalieri, F., Chiessi, E. et al. Poly(vinyl alcohol) as versatile biomaterial for potential biomedical applications. Journal of Materials Science: Materials in Medicine 14, 687–691 (2003). https://doi.org/10.1023/A:1024907615244

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  • DOI: https://doi.org/10.1023/A:1024907615244

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