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A simple single slice method for measurement of left and right ventricular enlargement by electron beam tomography

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Abstract

Rationale and objective:We devised to test the feasibility of measuring the left and right ventricular sizes by non-contrast electron beam tomographic images. Methods:Ventricular sizes consist of the sum of the intracavitary cavity and myocardial mass for each ventricle. A total of 50 image studies from subjects undergoing contrast-enhanced studies were used to develop the measurement methodology. About 20 contrast studies were used to test the measure. The methodology was then prospectively tested on 75 patients with non-contrast studies to estimate the intra-observer, inter-observer and inter-study reproducibility. Results:Multiple linear regression analysis was completed and the correct regression formulas to calculate ventricular volumes were acquired by using the area and span from the contrast studies. There was excellent correlation between the estimate of LV (r > 0.97, p < 0.001) and RV (r > 0.93, p < 0.001) sizes between measured and calculated (contrast, single slice) left and right ventricular volumes. The intra-observer, inter-observer and inter-study reproducibility demonstrated excellent results with <7% difference in absolute values and a high correlation (r > 0.89, p < 0.001). Conclusion:We conclude that the left and right ventricular sizes can be accurately estimated from a single mid-ventricular slice on non-contrast electron beam tomographic images.

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References

  1. Lee TH, Hamilton MA, Stevenson LW, et al. Impact of left ventricular cavity size on survival in advanced heart failure. Am J Cardiol 1993; 72: 672–676.

    Google Scholar 

  2. Abernethy M, Sharpe N, Smith H, Gamble G. Echocardiographic prediction of left ventricular volume after myocardial infarction. J Am Coll Cardiol 1991; 17: 1527–1532.

    Google Scholar 

  3. Kannel WB, Gordon T, Offutt D. Left ventricular hypertrophy by electrocardiogram: prevalence, incidence, and mortality in the Framingham study. Ann Intern Med 1969; 71: 89–105.

    Google Scholar 

  4. Levy D, Garrison RJ, Savage DD, Kanell WB, Castelli WP. Prognostic implications of echocardiographically determined left ventricular mass in the Framingham Heart Study. N Engl J Med 1990; 322: 1561–1566.

    Google Scholar 

  5. Ryan T, Petrovic O, Dillon JC, Feigenbaum H, Conley MJ, Amstrong WF. An echocardiographic index for separation of right ventricular volume and pressure overload. J Am Coll Cardiol 1985; 5: 918–924.

    Google Scholar 

  6. Schiller NB. Two-decisional echocardiographic determination of left ventricular volume, systolic function, and mass. Circulation 1991; 84: 280–287.

    Google Scholar 

  7. Byrd BF, Wahr D, Wang YS, Bouchard A, Schiller NB. Left ventricular mass and volume/mass ratio determined by two-dimensional echocardiography in normal adults. J Am Coll Cardiol 1985; 6: 1021–1025.

    Google Scholar 

  8. Horan LG, Flowers NC, Havelda CJ. Relation between right ventricular mass and cavity size: an analysis of 1500 human hearts. Circulation 1981; 64: 135–138.

    Google Scholar 

  9. Kennedy JW, Baxley WA, Figley MM, Dodge Ht, Blackmon JR. Quantitative angiocardiography. Circulation 1966; 34: 272–278.

    Google Scholar 

  10. Wynne J, Green LH, Levin D, Grossman W. Estimation of left ventricular volume in man from biplane cineangiogram filmed in oblique projects. Am J Cardiol 1978; 41: 726–732.

    Google Scholar 

  11. Hermann HJ, Bartle SH. Left ventricular volume by angiocardiography: comparison of methods and simplification of techniques. Cardiovasc Res 1968; 4: 404–414.

    Google Scholar 

  12. Kinboboye OO, Haines FA, Atkins HL, Oster ZH, Brown EJ. Assessment of left ventricular enlargement from planer thallium-201 images. Am Heart J 1994; 127: 148–151.

    Google Scholar 

  13. Varani MS, Owned J, LeBlanc AD, et al. Validation of left ventricular volume measurement by radionuclide angiography. J Nucl Med 1985; 26: 1394–1401.

    Google Scholar 

  14. Korr KS, Gandsman EJ, Winkler ML, Shulman RS, Bough EW. Hemodynamic correlates of right ventricular ejection fraction measure with gated radionuclide angiography. Am J Cardiol 1982; 49: 71–77.

    Google Scholar 

  15. Sechtem U, Pflugfelder PW, Gould RG, Cassity MM, Higgins CB. Measurement of right and left ventricular volumes in healthy individuals with cine MR imaging. Radiology 1987; 163: 697–702.

    Google Scholar 

  16. Stratemeier EJ, Thompson R, Brady TJ, et al. Ejection fraction determination by MR imaging: comparison with left ventricular angiography. Radiology 1986; 158: 775–777.

    Google Scholar 

  17. Heusch A, Koch JA, Krogmann ON, Korbmacher B, Bourgeois M. Volumetric analysis of the right and left ventricle in a porcine heart model: comparison of three-dimensional echocardiography, magnetic resonance imaging and angiocardiography. Eur J Ultrasound 1999; 9(3): 245–255.

    Google Scholar 

  18. Wachespress JD, Clarc NR, Untereker WJ, Kraushaar BT, Kurnik PB. Systolic and diastolic performance in normal human subjects as measured by ultrafast computed tomography. Cathet Cardiovasc Diagn 1988; 15: 277–283.

    Google Scholar 

  19. Bleiweis MS, Mao SS, Brundage BH. Total biventricular volume and total ventricular volume by ultrafast computed tomography: prediction of left ventricular mass. Am Heart J 1994; 127: 667–673.

    Google Scholar 

  20. Reiter SJ, Rumberger JA, Feiring AJ, Stanford W, Marcus ML. Precision of measurements of right and left ventricular volume by cine computed tomography. Circulation 1986; 74: 890–900.

    Google Scholar 

  21. Marzullo P, L‚‚abbte A, Marcus M. Patterns of global and regional systolic and diastolic function in the normal ventricle assessed by ultrafast tomography. J Am Coll Cardiol 1991; 17: 1318–1325.

    Google Scholar 

  22. Rumberger JA. Quantifying left ventricular regional and global systolic function using ultrafast computed tomography. Am J Cardiac Imaging 1991; 1: 29–37.

    Google Scholar 

  23. Georgiou D, Brundage BH. Conventional and ultrafast cine-computed tomography in cardiac imaging. Imaging and Echocardiography 1990; 5: 817–824.

    Google Scholar 

  24. Taylor AJ, O‚Malley PG. Self-referral of patients for electron-beam computed tomography to screen for coronary artery disease. N Engl J Med 1998; 339: 2018–2020.

    Google Scholar 

  25. Wang ND, Kouwabunpat D, Anthony N, et al. Coronary calcium and atherosclerosis by ultrafast computed tomography in asymptomatic men and women: relation to age and risk factors. Am Heart J 1994; 127: 422–430.

    Google Scholar 

  26. Froelicher V, Marrow K, Brown M, Atwood E, Marris C. Prediction of atherosclerotic cardiovascular death in men using prognostic score. Am J Cardiol 1994; 73: 133–138.

    Google Scholar 

  27. Budo. MJ, Georgiou D, Brody A, et al. Ultrafast computed tomography as a diagnostic modality in the detection of coronary artery disease, a multicenter study. Circulation 1996; 93: 898–904.

    Google Scholar 

  28. Arad Y, Spadaro LA, Goodman K, et al. Predictive value of electron beam computed tomography of the coronary arteries. 19–month follow-up of 1173 asymptomatic subjects. Circulation 1996; 93: 1951–1953.

    Google Scholar 

  29. Wexler L, Brundage BH, Crouse J, et al. Coronary artery calcification: pathophysiology, epidemiology, image methods, and clinical implications. A statement for health professionals from the American Heart Association. Circulation 1996; 94: 1175–1192.

    Google Scholar 

  30. Rumberger JA, Lipton M. Ultrafast CT scanning. Cardiology Clinics 1989; 7: 713–734.

    Google Scholar 

  31. Links JM, Becher LC, Shindledecker JG, et al. Measurement of absolute left volume from blood pool studies. Circulation 1982; 65: 82–90.

    Google Scholar 

  32. Haiduczok ZD, Weiss RM, Stanford W, Marcus ML. Determination of right ventricular mass in humans and dogs with ultrafast cardiac computed tomography. Circulation 1990; 82: 202–212.

    Google Scholar 

  33. Roig F, Georgiou D, Chomka EV, et al. Reproducibility of left ventricular myocardial volume and mass measurements by ultrafast computed tomography. J Am Coll Cardiol 1991; 18: 990–996.

    Google Scholar 

  34. Koren MJ, Devereux RB, Casale PN, Savage DD, Laragh JH. Relation of left ventricular mass and geometry to morbidity and mortality in uncomplicated essential hypertension. Ann Intern Med 1991; 114: 345–352.

    Google Scholar 

  35. Woo P, Mao S, Wang S, Detrano RC. Left ventricular size determined by electron beam computed tomography predicts significant coronary artery disease and events. Am J Cardiol 1997; 79: 1236–1238.

    Google Scholar 

  36. Rumberger JA, Behrenbeck T, Breen JR, Reed JE, Gersh BJ. Nonparallel changes in global left ventricular chamber volume and muscle mass during the first year after transmural myocardial infarction in humans. J Am Coll Cardiol 1993; 21: 673–682.

    Google Scholar 

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Authors and Affiliations

  1. The Saint John's Cardiovascular Research Center, USA

    Songshou Mao, Matthew J. Budoff, Ronald J. Oudiz, Hamid Bakhsheshi, ShaoJung Wang & Bruce H. Brundage

  2. Harbor-UCLA Medical Center, Torrance, California, USA

    Songshou Mao, Matthew J. Budoff, Ronald J. Oudiz, Hamid Bakhsheshi, ShaoJung Wang & Bruce H. Brundage

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  1. Songshou Mao
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  2. Matthew J. Budoff
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  4. Hamid Bakhsheshi
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  5. ShaoJung Wang
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  6. Bruce H. Brundage
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Mao, S., Budoff, M.J., Oudiz, R.J. et al. A simple single slice method for measurement of left and right ventricular enlargement by electron beam tomography. Int J Cardiovasc Imaging 16, 383–390 (2000). https://doi.org/10.1023/A:1026523924838

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