Abstract
A universal method for the synthesis of hydrophilic dendrimers was considered. The method is based on a combination of carbosilane dendrimers with different molecular organizations and hydrophilizing agents, viz., substituted hydride silanes containing one and three protected hydroxyl groups. The combination of a limited set of the mentioned reagents makes it possible to control the ratio of hydrophilic and hydrophobic moieties of the molecular structure in wide limits. A simple and convenient method for the removal of trimethylsilyl protection of hydroxyl groups in the surface layer of dendrimers was developed.
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Getmanova, E.V., Tereshchenko, A.S., Ignat"eva, G.M. et al. Diphilic carbosilane dendrimers with different densities of the hydrophilic layer. Russian Chemical Bulletin 53, 137–143 (2004). https://doi.org/10.1023/B:RUCB.0000024842.72905.c7
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DOI: https://doi.org/10.1023/B:RUCB.0000024842.72905.c7