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A Possible Explanation of the Relations between Hereditary Anæmias and Depigmentation in the Mouse

Abstract

IN mice there are two chief forms of hereditary anæmias, the macrocytic and the siderocytic or flexed tail anæmia1. The former is due to one of the dominants W or Wv, the first of which is lethal when homozygous while the second is viable. WW and WvWv animals are white with black eyes, and in the heterozygotes with the normal w the two factors may or may not show dominance, according to the factor concerned and the genetic background2. The other form of anæmia, the siderocytic, is due to the recessive factor f and is also associated with depigmentation. All the ff animals show a transitory anæmia at birth, and the majority of them have also a white spot on the belly and many times also a flexed tail.

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SERRA, J. A Possible Explanation of the Relations between Hereditary Anæmias and Depigmentation in the Mouse. Nature 159, 504–505 (1947). https://doi.org/10.1038/159504a0

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